Evidence map›Paper›PMID 29416687›Full record

ArticleOncotarget2018

No differences in brain microstructure between young KIBRA-C carriers and non-carriers.

Li Hu, Qunxing Xu, Jizhen Li, Feifei Wang, Xinghua Xu, Zhiyuan Sun, Xiangxing Ma, Yong Liu, Qing Wang, Dawei Wang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Li HuDepartment of Radiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Qunxing XuMedical Examination Center, Qilu Hospital of Shandong University, Jinan 250012, China.
Jizhen LiMental Health Center of Shandong Province, Jinan 250012, China.
Feifei WangDepartment of Radiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Xinghua XuDepartment of Radiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Zhiyuan SunDepartment of Radiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Xiangxing MaDepartment of Radiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Yong LiuBrainnetome Center, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
Qing WangDepartment of Radiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Dawei WangDepartment of Radiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Qilu Hospital of Shandong University · CNChinese Academy of Sciences · CNShandong Mental Health Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

KIBRA rs17070145 polymorphism is associated with variations in memory function and the microstructure of related brain areas. Diffusion kurtosis imaging (DKI) as an extension of diffusion tensor imaging that can provide more information about changes in microstructure, based on the idea that water diffusion in biological tissues is heterogeneous due to structural hindrance and restriction. We used DKI to explore the relationship between KIBRA gene polymorphism and brain microstructure in young adults. We recruited 100 healthy young volunteers, including 53 TT carriers and 47 C allele carriers. No differences were detected between the TT homozygotes and C-allele carriers for any diffusion and kurtosis parameter. These results indicate KIBRA rs17070145 polymorphism likely has little or no effect on brain microstructure in young adults.

Indexed as

brain microstructureDKIKIBRAyoung

Identifiers

PMID29416687
PMCPMC5787430
OpenAlexW2774133657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.