Evidence map›Paper›PMID 29416668›Full record

ArticleOncotarget2018

Molecular mechanisms of cardioprotective effects mediated by transplanted cardiac ckit

Giovanni Puddighinu, Domenico D'Amario, Eleonora Foglio, Melissa Manchi, Andrea Siracusano, Elena Pontemezzo, Martina Cordella, Francesco Facchiano, Laura Pellegrini, Antonella Mangoni and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Heart-derived endogenous stem cells.Molecular biology reports · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Giovanni PuddighinuDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Domenico D'AmarioDepartment of Cardiovascular Sciences, Catholic University of The Sacred Heart, Rome, Italy.
Eleonora FoglioDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Melissa ManchiDepartment of Cardiovascular Sciences, Catholic University of The Sacred Heart, Rome, Italy.
Andrea SiracusanoDepartment of Cardiovascular Sciences, Catholic University of The Sacred Heart, Rome, Italy.
Elena PontemezzoDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Martina CordellaDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
Francesco FacchianoDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
Laura PellegriniDepartment of Neurorehabilitation Sciences, Casa Cura Policlinico (CCP), Milan, Italy.
Antonella MangoniDepartment of Pathological Anatomy, Catholic University of The Sacred Heart, Rome, Italy.
Marco TafaniDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Filippo CreaDepartment of Cardiovascular Sciences, Catholic University of The Sacred Heart, Rome, Italy.
Antonia GermaniLaboratory of Vascular Pathology, Istituto Dermopatico dell'Immacolata, IDI-IRCCS, Fondazione Luigi Maria Monti, Rome, Italy.
Matteo Antonio RussoIRCCS San Raffaele Pisana, Rome, Italy.
Federica LimanaIRCCS San Raffaele Pisana, Rome, Italy.
Università Cattolica del Sacro Cuore · ITSapienza University of Rome · ITIstituto Superiore di Sanità · ITIRCCS Ospedale San Raffaele · ITIstituto Dermopatico dell'Immacolata · ITSan Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regenerative effects of cardiac ckit

Indexed as

cardiac repairckit+ stem cells and hypoxiainflammatory and reparative responsemolecular rehabilitationmyocardial infarction

Identifiers

PMID29416668
PMCPMC5787525
OpenAlexW2771409538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.