Evidence map›Paper›PMID 29416597›Full record

ArticleOncotarget2018

Peptide adjacent to glycosylation sites impacts immunogenicity of glycoconjugate vaccine.

Zhongrui Ma, Huajie Zhang, Peng George Wang, Xian-Wei Liu, Min Chen

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Zhongrui MaThe State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, School of Life Sciences, Shandong University, Jinan, Shandong, China.
Huajie ZhangThe State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, School of Life Sciences, Shandong University, Jinan, Shandong, China.
Peng George WangThe State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, School of Life Sciences, Shandong University, Jinan, Shandong, China.
Xian-Wei LiuThe State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, School of Life Sciences, Shandong University, Jinan, Shandong, China.
Min ChenThe State Key Laboratory of Microbial Technology, National Glycoengineering Research Center, School of Life Sciences, Shandong University, Jinan, Shandong, China.
Shandong University · CNGeorgia State University · US

Funding

Research and Development of a Novel System to Produce Polysaccharide Conjugate VaR01AI083754 · NIAID · OHIO STATE UNIVERSITY · PI WANG, PENG GEORGE · 2009 to 2016
$2.7M
NIAID NIH HHS R01 AI083754
6 · The paper itself

Abstract

Glycoconjugate vaccine is composed of polysaccharides (PSs) covalently linked with carrier protein. Glycosylation site selection, as a significant factor leading to heterogeneities of glycoconjugate structure, draws more and more attentions for its impact on the immunogenicity of glycoconjugate vaccine. To elucidate the relationship between glycosylation connectivity and immunogenicity of glycoconjugate vaccine, in this study, anti-

Indexed as

E. coli N-glycosylation systemglycoconjugate vaccineglycopeptideglycosylation siteimmunogenicityImmunology

Identifiers

PMID29416597
PMCPMC5787506
OpenAlexW2742292659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.