Evidence map›Paper›PMID 29416340›Full record

ArticleNeuropsychiatric disease and treatment2018

Self-stigma and treatment effectiveness in patients with anxiety disorders - a mediation analysis.

Marie Ociskova, Jan Prasko, Kristyna Vrbova, Petra Kasalova, Michaela Holubova, Ales Grambal, Klara Machu

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Article
  6. Association of self-stigma, impulsivity, and insomnia with anxiety and depression in patients with Kallmann syndrome.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  7. Article
  8. Self and other mental health stigma among public safety professionals: a psychometric study.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2025
    Review
  9. Assessing the dimensionality and construct validity of the military stigma scale across current service members.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marie OciskovaDepartment of Psychiatry, Faculty of Medicine and Dentistry, Palacky University, University Hospital, Olomouc.
Jan PraskoDepartment of Psychiatry, Faculty of Medicine and Dentistry, Palacky University, University Hospital, Olomouc.
Kristyna VrbovaDepartment of Psychiatry, Faculty of Medicine and Dentistry, Palacky University, University Hospital, Olomouc.
Petra KasalovaDepartment of Psychiatry, Faculty of Medicine and Dentistry, Palacky University, University Hospital, Olomouc.
Michaela HolubovaDepartment of Psychiatry, Faculty of Medicine and Dentistry, Palacky University, University Hospital, Olomouc.
Ales GrambalDepartment of Psychiatry, Faculty of Medicine and Dentistry, Palacky University, University Hospital, Olomouc.
Klara MachuDepartment of Psychology, Faculty of Arts, University of Ostrava, Ostrava, The Czech Republic.
University Hospital Olomouc · CZUniversity of Ostrava · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

goalThe goal of this study was to explore the impact of self-stigma on the treatment outcomes in patients with anxiety disorders and to find possible mediators of this relationship.

methodTwo hundred and nine patients with anxiety disorders, who were hospitalized in a psychotherapeutic department, attended the study. The average age was 39.2±12.4 years; two-thirds were women. Most of the patients used a long-term medication. The participants underwent either cognitive behavioral therapy (CBT) or short psychodynamic therapy. The selection to the psychotherapy was not randomized. All individuals completed several scales - Beck Depression Inventory, the second edition (BDI-II), Beck Anxiety Inventory (BAI), Dissociative Experience Scale (DES), Sheehan Disability Scale (SDS), subjective Clinical Global Impression (subjCGI), and The Internalized Stigma of Mental Illness Scale (ISMI). A senior psychiatrist filled out the objective CGI (objCGI).

resultsThe patients significantly improved in the severity of anxiety (BAI), depression (BDI-II), and overall severity of the mental disorder (objCGI). The self-stigma predicted a lower change of the objCGI, but not a change of the anxiety and depressive symptoms severity. Anxiety, depressive symptoms, dissociation, and disability were assessed as possible mediators of the relationship between the self-stigma and the treatment change. None of them were significant.

conclusionSelf-stigma lowers the effectiveness of the combined treatment of anxiety disorders. Future research should explore other possible mediators influencing this relationship.

Indexed as

anxiety disordersmedicationself-stigmatreatment effectiveness

Identifiers

PMID29416340
PMCPMC5790087
OpenAlexW2788679700

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.