ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2017
Hyperlactatemia and the Importance of Repeated Lactate Measurements in Critically Ill Patients.
Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Lactate abnormalities during intravenous linezolid therapy in hospitalized children: a brief report.European journal of pediatrics · 2026Article
- Potential Prognostic Parameters from Patient Medical Files for Inhalation Injury Presence and/or Degree: A Single-Center Study.European burn journal · 2025Article
- Mechanisms for Regulatory Effects of Exercise on Metabolic Diseases from the Lactate-Lactylation Perspective.International journal of molecular sciences · 2025Review
- Capillary lactate as a prognostic marker in sepsis: correlation with venous lactate and prediction of outcomes.BMC infectious diseases · 2025Article
- Risk factors for ICU-acquired weakness in sepsis patients: A retrospective study of 264 patients.Heliyon · 2024Article
- Linezolid-induced lactic acidosis.BMJ case reports · 2024Article
- Role of serum lactate as prognostic marker of mortality among emergency department patients with multiple conditions: A systematic review.SAGE open medicine · 2023Review
- Lactate and Lactate-to-Pyruvate Ratio in Critically Ill COVID-19 Patients: A Pilot Study.Journal of personalized medicine · 2022Article
- Identification and Quantitative Determination of Lactate Using Optical Spectroscopy-Towards a Noninvasive Tool for Early Recognition of Sepsis.Sensors (Basel, Switzerland) · 2020Article
- iTRAQ-based proteomic analysis reveals key proteins affecting cardiac function in broilers that died of sudden death syndrome.Poultry science · 2019Article
- Article
- Prognostic value of hyperlactatemia in infected patients admitted to intensive care units: a multicenter study.Revista Brasileira de terapia intensivaArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the study was to describe the prevalence of hyperlactatemia and emphasis on repeated lactate measurements in critically ill patients, and the associated mortality. MATERIALS AND
methodsThe study included 70 patients admitted in the Medical Intensive Care Unit at the Clinical Center, University of Sarajevo, in a 6-month period (July - December 2015). The following data were obtained: age, gender, reason for admission, Simplified Acute Physiology Score II, Acute Physiology and Chronic Health Evaluation, lactate concentrations upon admission, after 24 and 48 hours, and outcome (discharge from hospital or death).
resultsUpon admission,hyperlactatemia was present in 91.4% patients with a mean concentration of lactate 4.13 ±1.21 mmol/L. Lactate concentration at 48 hours was independently associated within creased in-hospital mortality (P = 0.018).
conclusionPersistent hyperlactatemia is associated with adverse outcome in critically ill patients. Lactate concentration at 48 hours is independently associated within creased in-hospital mortality and it represents a statistically significant predictive marker of fatal outcomes of patients. Blood lactate concentrations > 2.25 mmol/L should be used by clinicians to identify patients at higher risk of death.
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