Evidence map›Paper›PMID 29415760›Full record

ArticleTrials2018

Mobile critical care recovery program (m-CCRP) for acute respiratory failure survivors: study protocol for a randomized controlled trial.

Sikandar Khan, Ashok Biju, Sophia Wang, Sujuan Gao, Omar Irfan, Amanda Harrawood, Stephanie Martinez, Emily Brewer, Anthony Perkins, Frederick W Unverzagt and 5 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03053245 (Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03053245 nacompletednot on this map

Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors

TypeinterventionalSponsorIndiana UniversityRan2017 to 2022Enrolled503ConditionsAcute Respiratory Failure, Post-Intensive Care SyndromeArmsMobile Critical Care Program, Attention Control
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Observational
  6. Article
  7. The methodology of the Agile Nudge University.Frontiers in health services · 2023
    Article
  8. Article
  9. Article
  10. Caring for Survivors of Critical Illness: Current Practices and the Role of the Nurse in Intensive Care Unit Aftercare.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Sikandar KhanDivision of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. sikhan@iu.edu.ORCID http://orcid.org/0000-0003-4254-3436
Ashok BijuIU Center of Aging Research, Regenstrief Institute, Indianapolis, IN, USA.
Sophia WangDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Sujuan GaoDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA.
Omar IrfanAga Khan University, Karachi, Pakistan.
Amanda HarrawoodIU Center of Aging Research, Regenstrief Institute, Indianapolis, IN, USA.
Stephanie MartinezIU Center of Aging Research, Regenstrief Institute, Indianapolis, IN, USA.
Emily BrewerIU Center of Aging Research, Regenstrief Institute, Indianapolis, IN, USA.
Anthony PerkinsCenter of Health Innovation and Implementation Science, Center for Translational Science and Innovation, Indianapolis, IN, USA.
Frederick W UnverzagtDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Sue LasiterSchool of Nursing and Health Studies, University of Missouri, Kansas City, MO, USA.
Ben ZarzaurDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Omar RahmanDivision of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Malaz BoustaniIU Center of Aging Research, Regenstrief Institute, Indianapolis, IN, USA.
Babar KhanDivision of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Regenstrief Institute · USIndiana University School of MedicineAga Khan University · PKCenter for Innovation · USEskenazi Health Foundation · USUniversity of Missouri–Kansas City · US

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI LAHIRI, DEBOMOY K · 1991 to 2020
$37.3M
READI-SET-GO: Researching Efficient Approaches to Delirium Identification - Sustaining Effective Translation to create Gero-friendly OrganizationsR01AG030618 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI DONNA Marie FICK, EDWARD R MARCANTONIO · 2008 to 2026
$7.9M
IU Training Program in Molecular Physiology and Clinical Mechanisms of Lung DiseaseT32HL091816 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Erick Forno, Roberto F. Machado · 2009 to 2026
$4.3M
Brain Health Patient Safety Learning LaboratoryP30HS024384 · AHRQ · INDIANA UNIVERSITY INDIANAPOLIS · PI CALLAHAN, CHRISTOPHER M · 2015 to 2018
$3.8M
Decreasing Alzheimer's Disease and Related Dementias after Delirium-Exercise and Cognitive Training (DDD-ECT)R01AG055391 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI KHAN, BABAR A · 2017 to 2021
$3.5M
Mobile Critical Care Recovery Program (m-CCRP) for Acute Respiratory Failure (ARF) SurvivorsR01HL131730 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI KHAN, BABAR A · 2017 to 2021
$3.2M
Indiana University Dementia Screening Trial: The IU CHOICE StudyR01AG040220 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI BOUSTANI, MALAZ · 2012 to 2016
$2.8M
Longitudinal interactive vascular exposure and Alzheimer's DiseaseR01AG045350 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI GAO, SUJUAN · 2014 to 2016
$925k
Delirium Biomarkers in the Intensive Care UnitK23AG043476 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI KHAN, BABAR A · 2012 to 2016
$629k
AHRQ HHS P30 HS024384National Institutes of Health R01HL131730NHLBI NIH HHS R01 HL131730NHLBI NIH HHS T32 HL091816NIA NIH HHS K23 AG043476NIA NIH HHS P30 AG010133NIA NIH HHS R01 AG030618NIA NIH HHS R01 AG040220NIA NIH HHS R01 AG045350NIA NIH HHS R01 AG055391
6 · The paper itself

Abstract

backgroundPatients admitted to intensive care units (ICU) with acute respiratory failure (ARF) face chronic complications that can impede return to normal daily function. A mobile, collaborative critical care model may enhance the recovery of ARF survivors.

methodsThe Mobile Critical Care Recovery Program (m-CCRP) study is a two arm, randomized clinical trial. We will randomize 620 patients admitted to the ICU with acute respiratory failure requiring mechanical ventilation in a 1:1 ratio to one of two arms (310 patients per arm) - m-CCRP intervention versus attention control. Those in the intervention group will meet with a care coordinator after hospital discharge in predetermined intervals to aid in the recovery process. Baseline assessments and personalized goal setting will be used to develop an individualized care plan for each patient after discussion with an interdisciplinary team. The attention control arm will receive printed material and telephone reminders emphasizing mobility and management of chronic conditions. Duration of the intervention and follow-up is 12 months post-randomization. Our primary aim is to assess the efficacy of m-CCRP in improving the quality of life of ARF survivors at 12 months. Secondary aims of the study are to evaluate the efficacy of m-CCRP in improving function (cognitive, physical, and psychological) of ARF survivors and to determine the efficacy of m-CCRP in reducing acute healthcare utilization. DISCUSSION: The proposed randomized controlled trial will evaluate the efficacy of a collaborative critical care recovery program in accomplishing the Institute of Healthcare Improvement's triple aims of better health, better care, at lower cost. We have developed a collaborative critical care model to promote ARF survivors' recovery from the physical, psychological, and cognitive impacts of critical illness. In contrast to a single disease focus and clinic-based access, m-CCRP represents a comprehensive, accessible, mobile, ahead of the curve intervention, focused on the multiple aspects of the unique recovery needs of ARF survivors.

trial registrationNCT03053245 , clinicaltrials.gov, registered February 1, 2017.

Indexed as

Patient Care PlanningAcute DiseaseCognitionCognitive Behavioral TherapyCombined Modality TherapyCritical CareExerciseFemaleHumansIndianaIntensive Care UnitsMaleMental HealthPatient Care TeamPatient DischargeQuality of LifeCognitive impairmentCognitive trainingCritical careDeliriumICU survivorshipPhysical activityPost-intensive care syndromeQuality of life

Identifiers

PMID29415760
PMCPMC5803999
OpenAlexW2785314904

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.