Trial reportBMC pediatrics2018
Performance of anthropometric indicators as predictors of metabolic syndrome in Brazilian adolescents.
Trial report in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Epidemiological Impact of Metabolic Syndrome in Overweight and Obese European Children and Adolescents: A Systematic Literature Review.Nutrients · 2023Pooled it
- Profile and predictors of metabolic syndrome among young adults attending a Medical College in Quetta City, Pakistan.Journal of pharmaceutical policy and practice · 2026Article
- Physical Fitness and Health Profile of Adolescents Living in Amazonas.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Using weight-for-age as a screening tool for metabolic syndrome in apparently healthy adolescents.Pediatric research · 2025Article
- Machine Learning-Based predictive model for adolescent metabolic syndrome: Utilizing data from NHANES 2007-2016.Scientific reports · 2025Article
- Prevalence of dyslipidemia and predictive value of anthropometric indicators among children and adolescents in the Tibetan Plateau.Frontiers in nutrition · 2025Article
- Study on the association between visceral adiposity index and diabetic kidney disease in hospitalized patients with type 2 diabetes mellitus in China.Frontiers in endocrinology · 2025Article
- Article
- The Association Between Obesity Measures and Metabolic Syndrome Risk in Korean Adolescents Aged 10-18 Years.Journal of multidisciplinary healthcare · 2024Article
- Comparison of Diagnostic Models to Estimate the Risk of Metabolic Syndrome in a Chilean Pediatric Population: A Cross-Sectional Study.Metabolites · 2023Article
- Diagnostic performance of central and generalized adiposity in detecting risk of diabetes mellitus in adolescents.African health sciences · 2022Article
- A Multivariate Analysis of "Metabolic Phenotype" Patterns in Children and Adolescents with Obesity for the Early Stratification of Patients at Risk of Metabolic Syndrome.Journal of clinical medicine · 2022Article
- Using noninvasive anthropometric indices to develop and validate a predictive model for metabolic syndrome in Chinese adults: a nationwide study.BMC endocrine disorders · 2022Article
- Value of Adding Bioelectrical Impedance Analysis to Anthropometric Indices in the Diagnosis of Metabolic Syndrome in 10-16 Years Old Schoolgirls.Healthcare (Basel, Switzerland) · 2022Article
- Associations between negative gender attitudes and eating behaviors in Chinese children and adolescents.Frontiers in nutrition · 2022Article
- Predictive Ability of the Estimate of Fat Mass to Detect Early-Onset Metabolic Syndrome in Prepubertal Children with Obesity.Children (Basel, Switzerland) · 2021Article
- Performance of waist-to-height ratio as a screening tool for identifying cardiometabolic risk in children: a meta-analysis.Diabetology & metabolic syndrome · 2021Article
- Sex-Specific Differences in the Relationship between Insulin Resistance and Adiposity Indexes in Children and Adolescents with Obesity.Children (Basel, Switzerland) · 2021Article
- Anthropometry did not approach adequate predictive accuracies for detecting elevated fasting plasma glucose or hemoglobin A1c levels among Chinese children aged 7-9 years.Journal of diabetes investigation · 2021Article
- Waist Circumference Is Not Associated with Impaired Fasting Blood Glucose in a Sample of Mexican Children and Teenagers: Results from a State Screening Program.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is not clear which is the best anthropometric indicator to predict metabolic syndrome (MetS) in adolescents. Our objective was to identify the predictive power, with respective cut-off points, of anthropometric indicators associated with the quantity and distribution of body fat for the presence of MetS and to determine the strength of the association between the proposed cut-off points and MetS in adolescents.
methodsThe sample consisted of 1035 adolescents (565 girls and 470 boys) aged between 12 and 20 years. Four anthropometric indicators were considered: waist circumference (WC), body mass index (BMI), waist-height ratio (WHtR), and conicity index (C-Index). MetS was defined according to the criteria of the International Diabetes Federation. Predictive performance was described through analysis of Receiver Operating Characteristic (ROC) curves with a 95% confidence interval. The most accurate cut-off points were identified through sensitivity, specificity and Area Under the Curve (AUC) values.
resultsThe four anthropometric indicators presented significant AUCs close to 0.70. At younger ages (12-15 years) the girls presented a statistically greater capacity to discriminate MetS; however, at more advanced ages (16-20 years) both sexes presented similar AUCs. Among the anthropometric indicators investigated, regardless of sex and age, the WHtR showed the highest discriminant value for MetS, while the C-Index demonstrated a significantly lower capacity to predict MetS. The AUCs equivalent to WC and BMI did not differ statistically. The proposed cut-off points for WHtR (12-15 years = 0.46, 16-20 years = 0.48) presented the highest values of sensitivity and specificity, between 60% and 70%, respectively.
conclusionConsidering that the best AUC was found for WHtR, we suggest the use of this anthropometric indicator, with the cut-off points presented herein, for the prediction of MetS in adolescents with characteristics similar to the study sample.
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