ArticleJournal of radiation research2018
Incidence of organizing pneumonia after whole-breast radiotherapy for breast cancer, and risk factor analysis.
Article in Journal of radiation research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and prevalence of interstitial lung diseases worldwide: a systematic literature review.BMJ open respiratory research · 2023Pooled it
- Metastatic Breast Cancer Presenting as an Organizing Pneumonia Pattern on Chest CT: A Case Report.Cureus · 2026Article
- Cryobiopsy for diagnosing acute fibrinous and organizing pneumonia during breast cancer treatment: A case report.Experimental and therapeutic medicine · 2025Article
- Secondary Organizing Pneumonia: A Case Report of a Noteworthy Complication of Breast Irradiation.Cureus · 2025Article
- Dosimetric analysis of six whole-breast irradiation techniques in supine and prone positions.Scientific reports · 2024Article
- Article
- Radiation-induced organizing pneumonia caused by carbon-ion radiotherapy for lung cancer.Radiology case reports · 2024Article
- Organising pneumonia caused by hormone (tamoxifen) therapy after radiotherapy for breast cancer: a case report and review of the literature.Annals of translational medicine · 2023Article
- MicroRNA: a novel implication for damage and protection against ionizing radiation.Environmental science and pollution research international · 2021Review
- Spontaneous resolution of thoracic radiation therapy-induced organizing pneumonia: A case series.Respiratory medicine case reports · 2019Article
- Breast cancer and organising pneumonia: the importance of correlating the pathological findings with the clinical and radiological picture.BMJ case reports · 2018Article
- Radiation Dermatitis and Pneumonitis in Patients Irradiated for Breast Cancer.In vivo (Athens, Greece)Article
- Factors Associated With Radiation Pneumonitis in Patients Receiving Electron Boost Radiation for Breast-Conserving Therapy: A Retrospective Review.Advances in radiation oncologyArticle
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7 authors.
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Abstract
Radiation-induced organizing pneumonia (OP) reportedly occurs in ~2% of patients who receive whole-breast radiotherapy (WBRT). Though there are several reported risk factors, they remain unclear and controversial. We analyzed the incidence of and risk factors for OP after WBRT at our institution. We analyzed 665 breast cancer patients (with WBRT of 679 breasts) who underwent WBRT from October 2007 to September 2012 at our institution and were followed up for more than 1 year after completion of WBRT. Factors included in the analysis were age, the side affected, central lung distance (CLD), radiation dose, concurrent endocrine therapy, and chemotherapy. The median age was 56 years (range, 23-89 years). The sides affected were left, right and bilateral in 342, 309 and 14 patients, respectively. The median CLD was 1.1 cm (range, 0-3.0 cm). Concurrent endocrine therapy was performed in 236 patients, and chemotherapy was given in 215 patients; of these, 4 received concurrent chemotherapy. OP developed in nine patients (1.4%). The median time taken to develop OP after the completion of WBRT was 4 months (range, 2-12 months). All nine patients were treated with steroids, and symptoms promptly improved, except in two patients who relapsed. Statistical analysis revealed that only CLD (≥1.5 cm) was significantly associated with the development of OP (P = 0.004). In conclusion, the incidence of OP after WBRT was 1.4%, and CLD was a significant risk factor. In these patients, OP was controlled with steroid administration.
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