Evidence map›Paper›PMID 29414882›Full record

ArticleToxins2018

PhcrTx2, a New Crab-Paralyzing Peptide Toxin from the Sea Anemone Phymanthus crucifer.

Armando Alexei Rodríguez, Anoland Garateix, Emilio Salceda, Steve Peigneur, André Junqueira Zaharenko, Tirso Pons, Yúlica Santos, Roberto Arreguín, Ludger Ständker, Wolf-Georg Forssmann and 3 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Isolation and cDNA cloning of four peptide toxins from the sea anemoneThe journal of venomous animals and toxins including tropical diseases · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 7 countries.

Armando Alexei RodríguezCore Facility Functional Peptidomics, Ulm University Medical Center, Albert-Einstein-Allee 47, 89081 Ulm, Germany. armando.rodriguez-alfonso@uni-ulm.de.ORCID 0000-0001-5921-3770
Anoland GarateixCentro de Bioproductos Marinos (CEBIMAR), Loma y 37, Alturas del Vedado, Habana CP 10600, Cuba. agarateix@gmail.com.
Emilio SalcedaInstituto de Fisiología, Benemérita Universidad Autónoma de Puebla, 14 sur 6301, CU, San Manuel, Puebla CP 72750, Mexico. ludger.staendker@uni-ulm.de.
Steve PeigneurToxicology & Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg O&N2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium. Steve.Peigneur@pharm.kuleuven.be.ORCID 0000-0003-0504-5702
André Junqueira ZaharenkoLaboratory of Genetics, Butantan Institute, São Paulo 05503-900, Brazil. a.j.zaharenko@gmail.com.
Tirso PonsCentro Nacional de Biotecnología (CNB-CSIC), Departamento de Inmunología y Oncología, C/Darwin 3, Campus de Cantoblanco, 28049 Madrid, Spain. tpons@cnb.csic.es.ORCID 0000-0002-7616-7750
Yúlica SantosDepartment of Plant Pathology, Citrus Research and Education Center, University of Florida, Lake Alfred, FL 33850, USA. yulica_santos@yahoo.com.
Roberto ArreguínInstituto de Química, Universidad Nacional Autónoma de México, Delegación Coyoacán, Ciudad de México 04510, Mexico. arrespin@gmail.com.
Ludger StändkerCore Facility Functional Peptidomics, Ulm University Medical Center, Albert-Einstein-Allee 47, 89081 Ulm, Germany. ludger.staendker@uni-ulm.de.
Wolf-Georg ForssmannDepartment of Experimental and Clinical Peptide Chemistry, Hannover Medical School (MHH), Feodor-Lynen-Straße 31, D-30625 Hannover, Germany. wg.forssmann@pharis.de.
Jan TytgatToxicology & Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg O&N2, Herestraat 49, P.O. Box 922, 3000 Leuven, Belgium. Jan.Tytgat@pharm.kuleuven.be.
Rosario VegaInstituto de Fisiología, Benemérita Universidad Autónoma de Puebla, 14 sur 6301, CU, San Manuel, Puebla CP 72750, Mexico. axolotl_56@yahoo.com.mx.
Enrique SotoInstituto de Fisiología, Benemérita Universidad Autónoma de Puebla, 14 sur 6301, CU, San Manuel, Puebla CP 72750, Mexico. esoto24@gmail.com.ORCID 0000-0003-2428-7416
Benemérita Universidad Autónoma de Puebla · MXKU Leuven · BEUniversität Ulm · DECentro Nacional de Biopreparados (Cuba) · CUCentro Nacional de Biotecnología · ESFlorida Department of Citrus · USInstituto Butantan · BRMedizinische Hochschule Hannover · DEUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sea anemones produce proteinaceous toxins for predation and defense, including peptide toxins that act on a large variety of ion channels of pharmacological and biomedical interest.

Indexed as

Sea AnemonesAnimalsBrachyuraGanglia, SpinalIon ChannelsNeuronsNeurotoxinsParalysisRats, WistarSnailsIon ChannelsNeurotoxinsdefensin-like foldglutamate receptorion channelsneutoxinPhymanthus crucifersea anemone

Identifiers

PMID29414882
PMCPMC5848173
OpenAlexW2789248935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.