ArticleJournal of lipid research2018
Production of lipid mediators across different disease stages of dextran sodium sulfate-induced colitis in mice.
Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Tracing NADCell reports · 2026Article
- Seal and fish oils partially counteract inflammation and modulate endocannabinoidome lipid and oxylipin alterations in DSS-induced colitis.Scientific reports · 2026Article
- An In Silico Omics Investigation of the Lactobacillus Genus Complex for Allergenicity Mitigation.Immunity, inflammation and disease · 2026Article
- Tracing NADResearch square · 2025Article
- Targeting intestinal inflammation using locked nucleic acids delivered via lipid nanoparticles.Nature communications · 2025Article
- Sex hormone deprivation abolishes sex-specific differences in murine colon inflammation and related lipid mediator production.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Alleviation of allergic conjunctivitis by (±)5(6)-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid in mice.Frontiers in pharmacology · 2023Article
- Protective Effects of Protopanaxatriol Saponins on Ulcerative Colitis in Mouse Based on UPLC-Q/TOF-MS Serum and Colon Metabolomics.Molecules (Basel, Switzerland) · 2022Article
- Involvement of Proinflammatory Arachidonic Acid (ARA) Derivatives in Crohn's Disease (CD) and Ulcerative Colitis (UC).Journal of clinical medicine · 2022Article
- Efficient Attenuation of Dextran Sulfate Sodium-Induced Colitis by Oral Administration of 5,6-Dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic Acid in Mice.International journal of molecular sciences · 2021Article
- The complex role of prostaglandin EAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2021Review
- The Aryl Hydrocarbon Receptor (AHR) as a Potential Target for the Control of Intestinal Inflammation: Insights from an Immune and Bacteria Sensor Receptor.Clinical reviews in allergy & immunology · 2020Review
- Fatty acid metabolism in the host and commensal bacteria for the control of intestinal immune responses and diseases.Gut microbes · 2020Review
- Article
- The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease.Mediators of inflammation · 2019Review
- Calcium/calmodulin-dependent protein kinase IV (CaMKIV) activation contributes to the pathogenesis of experimental colitis via inhibition of intestinal epithelial cell proliferation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019Article
- 5,6-DiHETE attenuates vascular hyperpermeability by inhibiting CaJournal of lipid research · 2018Article
- Frondanol, a Nutraceutical Extract fromMarine drugs · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although several studies have revealed the role of different lipid mediators in colitis, the comprehensive analysis of their production across different phases of colitis remained unclear. Here, we performed the following analysis in the dextran sodium sulfate (DSS)-induced colitis model using LC-MS/MS. Oral administration of 2% DSS in mice for 4 days resulted in severe intestinal inflammation by day 7, which gradually subsided by day 18. Based on the disease scoring index (assigned on the basis of fecal condition and weight loss), we defined the phases of colitis as induction (days 0-4), acute inflammation (days 4-7), recovery (days 7-9), and late recovery (days 9-18). Across all phases, 58 lipid mediators were detected in the inflamed colon tissue. In the induction phase, the production of n-6 fatty acid-derived prostaglandin E
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