Evidence map›Paper›PMID 29414704›Full record

ArticleBiophysical journal2018

Protein Dynamics of the Sensor Protein HemAT as Probed by Time-Resolved Step-Scan FTIR Spectroscopy.

Andrea Pavlou, Hideaki Yoshimura, Shigetoshi Aono, Eftychia Pinakoulaki

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PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The incorporation of MgFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea PavlouDepartment of Chemistry, University of Cyprus, Nicosia, Cyprus.
Hideaki YoshimuraInstitute for Molecular Science, Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences, Myodaiji, Okazaki, Japan.
Shigetoshi AonoInstitute for Molecular Science, Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences, Myodaiji, Okazaki, Japan.
Eftychia PinakoulakiDepartment of Chemistry, University of Cyprus, Nicosia, Cyprus. Electronic address: effiep@ucy.ac.cy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heme-based aerotactic transducer (HemAT) is an oxygen-sensor protein consisting of a sensor and a signaling domain in the N- and C-terminal regions, respectively. Time-resolved step-scan FTIR spectroscopy was employed to characterize protein intermediate states obtained by photolysis of the carbon monoxide complexes of sensor-domain, full-length HemAT, and the Y70F (B-helix), L92A (E-helix), T95A (E-helix), and Y133F (G-helix) HemAT mutants. We assign the spectral components to discrete substructures, which originate from a helical structure that is solvated (1638 cm

Indexed as

Bacillus subtilisBacterial ProteinsCarbon MonoxideHeme-Binding ProteinsHemeproteinsKineticsModels, MolecularOxygenProtein ConformationSpectroscopy, Fourier Transform InfraredBacterial ProteinsCarbon MonoxideHeme-Binding Proteinsheme protein, bacteriaHemeproteinsOxygen

Identifiers

PMID29414704
PMCPMC5985031

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.