ReviewBiophysical journal2018
Dynamics of Posttranslational Modification Systems: Recent Progress and Future Directions.
Review in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 53 citations in OpenAlex.
- Review
- Protein palmitoylation: an emerging regulator of inflammatory signaling and diseases.Frontiers in immunology · 2025Review
- The Inheritance of Local Bifurcations in Mass Action Networks.Journal of nonlinear science · 2025Article
- In distributive phosphorylation catalytic constants enable non-trivial dynamics.Journal of mathematical biology · 2024Article
- Selective recognition and discrimination of single isomeric changes in peptide strands with a host : guest sensing array.Chemical science · 2024Article
- Article
- Nutrient Deficiencies Impact on the Cellular and Metabolic Responses of Saxitoxin ProducingMarine drugs · 2023Article
- Benchmarking tools for a priori identifiability analysis.Bioinformatics (Oxford, England) · 2023Article
- Network regulation meets substrate modification chemistry.Journal of the Royal Society, Interface · 2023Article
- Review
- Genetic Analysis ofGenes · 2022Review
- Emerging roles of protein palmitoylation and its modifying enzymes in cancer cell signal transduction and cancer therapy.International journal of biological sciences · 2022Review
- Symmetry breaking meets multisite modification.eLife · 2021Article
- Article
- Article
- Exploring cyclic networks of multisite modification reveals origins of information processing characteristics.Scientific reports · 2020Article
- Joining and decomposing reaction networks.Journal of mathematical biology · 2020Article
- The interplay of spatial organization and biochemistry in building blocks of cellular signalling pathways.Journal of the Royal Society, Interface · 2020Article
- A computational framework for a Lyapunov-enabled analysis of biochemical reaction networks.PLoS computational biology · 2020Article
- Oscillations and bistability in a model of ERK regulation.Journal of mathematical biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Posttranslational modification of proteins is important for signal transduction, and hence significant effort has gone toward understanding how posttranslational modification networks process information. This involves, on the theory side, analyzing the dynamical systems arising from such networks. Which networks are, for instance, bistable? Which networks admit sustained oscillations? Which parameter values enable such behaviors? In this Biophysical Perspective, we highlight recent progress in this area and point out some important future directions. Along the way, we summarize several techniques for analyzing general networks, such as eliminating variables to obtain steady-state parameterizations, and harnessing results on how incorporating intermediates affects dynamics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.