ArticleTranslational oncology2018
Therapeutic Effect of α-Emitting
Article in Translational oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Emergence of a barium metal-organic framework for mitigating off-target effects of alpha radionuclide therapy.Theranostics · 2026Article
- Development ofDrug delivery and translational research · 2026Article
- Targeted Radium Alpha Therapy in the Era of Nanomedicine: In Vivo Results.International journal of molecular sciences · 2024Review
- Microfluidically Assisted Synthesis of Calcium Carbonate Submicron Particles with Improved Loading Properties.Micromachines · 2023Article
- Disordered Crystal Structure and Anomalously High Solubility of Radium Carbonate.Inorganic chemistry · 2023Article
- Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology.EJNMMI radiopharmacy and chemistry · 2022Review
- Intraperitoneal alpha therapy withFrontiers in medicine · 2022Article
- A Novel Single-Step-LabeledMaterials (Basel, Switzerland) · 2021Article
- Improved Formulation ofPharmaceutics · 2021Article
- Ra-224 activity, half-life, and 241 keV gamma ray absolute emission intensity: A NIST-NPL bilateral comparison.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2021Article
- Radon-220 diffusion from 224Ra-labeled calcium carbonate microparticles: Some implications for radiotherapeutic use.PloS one · 2021Article
- Primary standardization ofApplied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2020Article
- Development of Targeted Alpha Particle Therapy for Solid Tumors.Molecules (Basel, Switzerland) · 2019Review
- Efficacy and safety of intraperitoneally administered resveratrol against rat orthotopic ovarian cancers.Cancer management and research · 2019Article
- Correlation of the absorbed dose to the blood and DNA damage in leukocytes after internal ex-vivo irradiation of blood samples with Ra-224.EJNMMI research · 2018Article
- Ra-224 labeling of calcium carbonate microparticles for internal α-therapy: Preparation, stability, and biodistribution in mice.Journal of labelled compounds & radiopharmaceuticals · 2018Article
- Progress in Targeted Alpha-Particle Therapy. What We Learned about Recoils Release from In Vivo Generators.Molecules (Basel, Switzerland) · 2018Review
- Physiology and Pathology of Contractility of the Myometrium.In vivo (Athens, Greece)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOvarian cancer patients with chemotherapy-resistant residual microscopic disease in the peritoneal cavity have a considerable need for new treatment options. Alpha-emitting radionuclides injected intraperitoneally may be an attractive therapeutic option in this situation as they are highly cytotoxic, while their short range in tissues can spare surrounding radiosensitive organs in the abdomen. Herein we evaluate the therapeutic efficacy of a novel α-emitting compound specifically designed for intracavitary radiation therapy.
methodsThe α-emitter
resultsIn both models, intraperitoneal treatment with
conclusionsIntraperitoneal α-therapy with
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.