ArticleThe Kaohsiung journal of medical sciences2018
Microdissection testicular sperm extraction (micro-TESE): Predictive value of preoperative hormonal levels and pathology in non-obstructive azoospermia.
Article in The Kaohsiung journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- An examination of predictive markers for successful sperm extraction procedures: a linear model and systematic review.Asian journal of andrologyPooled it
- A common cause of non-obstructive azoospermia: biallelic MEI1 variants and implications for infertility diagnostics.Journal of assisted reproduction and genetics · 2026Article
- Global Andrology Forum (GAF) Clinical Guidelines on the Management of Non-obstructive Azoospermia: Bridging the Gap between Controversy and Consensus.The world journal of men's health · 2026Article
- Anatomical considerations, testicular, and scrotal anatomy of nonobstructive azoospermia patients.Asian journal of andrology · 2025Review
- The Small RNA Landscape in Azoospermia: Implications for Male Infertility and Sperm Retrieval-A Preliminary Study.International journal of molecular sciences · 2025Article
- CITED2 Binding to EP300 Regulates Human Spermatogonial Stem Cell Proliferation and Survival Through HSPA6.Stem cells international · 2025Article
- Predictors of Successful Testicular Sperm Extraction: A New Era for Men with Non-Obstructive Azoospermia.Biomedicines · 2024Review
- Role of Follicle-stimulating Hormone, Inhibin B, and Anti-Müllerian Hormone in Predicting Sperm Retrieval from Men with Nonobstructive Azoospermia Undergoing Microdissection Testicular Sperm Extraction: A Systematic Review and Meta-analysis.European urology open science · 2024Review
- Does Clomiphene citrate administration increase the success rate of microdissection testicular sperm extraction in non-obstructive azoospermic men? A cross-sectional study.International journal of reproductive biomedicine · 2023Article
- Evaluating the Predictive Value of Diagnostic Testicular Biopsy for Sperm Retrieval Outcomes in Men with Non-Obstructive Azoospermia.Journal of personalized medicine · 2023Article
- Testicular sperm aspiration has a poor effect in predicting micro-TESE outcomes in NOA patients with AZFc deletion.Basic and clinical andrology · 2023Article
- Staged Laboratory Processing of Testicular Tissue in Non-Obstructive Azoospermia May Rescue Retrieving an Existing Sperm: A Case Report and Literature Review.Clinical medicine insights. Case reports · 2023Article
- Factors predicting successful sperm retrieval in men with nonobstructive Azoospermia: A single center perspective.Health science reports · 2022Article
- Nomogram based on a circular RNA biomarker for predicting the likelihood of successful sperm retrievalFrontiers in endocrinology · 2022Article
- Microdissection testicular sperm extraction (micro-TESE) in men with infertility due to nonobstructive azoospermia: summary of current literature.International urology and nephrology · 2021Review
- Success rate and ART outcome of microsurgical sperm extraction in non obstructive azoospermia: A retrospective study.International journal of reproductive biomedicine · 2021Article
- Hormonal markers as noninvasive predictors of sperm retrieval in non-obstructive azoospermia.Journal of assisted reproduction and genetics · 2021Review
- Predictors of surgical sperm retrieval in non-obstructive azoospermia: summary of current literature.International urology and nephrology · 2020Review
- Analysis of factors affecting repeat microdissection testicular sperm extraction outcomes in infertile men.Turkish journal of urology · 2019Article
- Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the predictive value of preoperative hormonal levels and pathology, as well as the outcome of microsurgical testicular sperm extraction in patients with non-obstructive azoospermia (NOA), presenting to our clinic for treatment of infertility. The records of 145 men with NOA who underwent microdissection testicular sperm extraction (micro-TESE) between March 2013 and November 2016 were studied. The patient's age, testicular volume, hormonal profile for follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (TT), and testicular pathology were recorded. The sperm retrieval, the clinical pregnancy and live birth delivery rates were noted. Our testicular sperm retrieval rate was 65.5%. There was no statistical difference in age, testicular volume, or hormonal levels in the TESE-positive and negative groups. Hypospermatogenesis was found in testicular histopathology in 57 of 117 patients (48.7%) who underwent testicular biopsy. Sertoli Cell-Only (SCO) syndrome was seen in 20.5%, Germ Cell Maturation Arrest (MA) in 16.3%, and Atrophy-hyalinization in 14.5%. Seven men had Klinefelter's syndrome (KS), four of whom were TESE-positive. There were no adverse effects of the procedure except for infection at the incision site in one patient. Single intracytoplasmic sperm injection (ICSI) cycles were performed in 92 couples leading to 41 clinical pregnancies and 26 live birth deliveries. Micro-TESE is a safe procedure in experienced hands and provides infertile men with NOA an opportunity to father children. However unselected candidates with NOA should be counselled at the outset that only 17.9% will eventually become biological fathers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.