Evidence map›Paper›PMID 29413014›Full record

ReviewGastroenterology clinics of North America2018

The Need to Reassess Dietary Fiber Requirements in Healthy and Critically Ill Patients.

Stephen J D O'Keefe

Abstract readReview
In one paragraph

Review in Gastroenterology clinics of North America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. The gut microbiome in feast and famine.Nature reviews. Gastroenterology & hepatology · 2021
    Article
  8. Fiber in the ICU: Should it Be a Regular Part of Feeding?Current gastroenterology reports · 2021
    Review
  9. Going with the grain: Fiber, cognition, and the microbiota-gut-brain-axis.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Stephen J D O'KeefeDivision of Gastroenterology and Nutrition, Department of Medicine, University of Pittsburgh, 853 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15213, USA. Electronic address: sjokeefe@pitt.edu.

Funding

Randomized Controlled Trial of Resistant Starch to Reduce Colon Cancer Risk in Alaska Native PeopleR01CA204403 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI O'KEEFE, STEPHEN J.D., THOMAS, TIMOTHY K · 2017 to 2021
$2.8M
Diet and Gastrointestinal Cancer Risk in African Americans and Rural AfricansR01CA135379 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI O'KEEFE, STEPHEN J.D. · 2009 to 2012
$2.1M
NCI NIH HHS R01 CA135379NCI NIH HHS R01 CA204403
6 · The paper itself

Abstract

This article provides evidence that current dietary fiber intake levels may be insufficient to maintain colonic mucosal health and defense, and reduce inflammation and cancer risk in otherwise healthy people. Current commercial tube feeds generally overlook the metabolic needs of the colon and may predispose patients to dysbiosis, bacterial overgrowth with pathogens such as Clostridium difficile, and acute colitis. These results raise concern about the wide-scale use of prophylactic antibiotics in the intensive care unit and the use of elemental, fiber-depleted tube feeds. Nutrition support is not complete without the addition of sufficient fiber to meet colonic nutritional needs.

Indexed as

Critical IllnessDietary SupplementsHealthDietary FiberHumansNutritional RequirementsDietary FiberClinical studiesClostridium difficileColon cancerDietary fiberFiber supplementation

Identifiers

PMID29413014
PMCPMC6312100

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.