Evidence map›Paper›PMID 29411648›Full record

ReviewCritical reviews in biochemistry and molecular biology2018

Expanding the boundary of biocatalysis: design and optimization of in vitro tandem catalytic reactions for biochemical production.

Yajie Wang, Hengqian Ren, Huimin Zhao

Open access · greenAbstract readReview
In one paragraph

Review in Critical reviews in biochemistry and molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Markov-State Transition Path Analysis of Electrostatic Channeling.The journal of physical chemistry. C, Nanomaterials and interfaces · 2019
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yajie Wanga Department of Chemical and Biomolecular Engineering , University of Illinois at Urbana-Champaign , Urbana , IL , USA.
Hengqian Rena Department of Chemical and Biomolecular Engineering , University of Illinois at Urbana-Champaign , Urbana , IL , USA.
Huimin Zhaoa Department of Chemical and Biomolecular Engineering , University of Illinois at Urbana-Champaign , Urbana , IL , USA.ORCID 0000-0002-9069-6739
University of Illinois Urbana-Champaign · US

Funding

Structural Elucidation and Biosynthesis P01GM077596 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI METCALF, WILLIAM W · 2007 to 2016
$15.3M
NIGMS NIH HHS P01 GM077596
6 · The paper itself

Abstract

Biocatalysts have been increasingly used in the synthesis of fine chemicals and medicinal compounds due to significant advances in enzyme discovery and engineering. To mimic the synergistic effects of cascade reactions catalyzed by multiple enzymes in nature, researchers have been developing artificial tandem enzymatic reactions in vivo by harnessing synthetic biology and metabolic engineering tools. There is also growing interest in the development of one-pot tandem enzymatic or chemo-enzymatic processes in vitro due to their neat and concise catalytic systems and product purification procedures. In this review, we will briefly summarize the strategies of designing and optimizing in vitro tandem catalytic reactions, highlight a few representative examples, and discuss the future trend in this field.

Indexed as

BiocatalysisModels, ChemicalEnzymesMetabolic EngineeringSynthetic BiologyEnzymeschemoenzymaticEnzymaticin vitromultisteptandem

Identifiers

PMID29411648
PMCPMC6112242
OpenAlexW2790748734

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.