Evidence map›Paper›PMID 29411255›Full record

ArticleMaternal and child health journal2018

Advanced Maternal Age and Maternal Education Disparity in Children with Autism Spectrum Disorder.

For-Wey Lung, Tung-Liang Chiang, Shio-Jean Lin, Meng-Chih Lee, Bih-Ching Shu

Abstract read
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Article in Maternal and child health journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Predicting 18-month M-CHAT-R/F With PediaTracJournal of autism and developmental disorders · 2026
    Article
  2. Article
  3. Sex-Based Differences in Prenatal and Perinatal Predictors of Autism Spectrum Disorder Using Machine Learning With National Health Data.Autism research : official journal of the International Society for Autism Research · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

For-Wey LungCalo Psychiatric Center, Pingtung County, Taiwan.
Tung-Liang ChiangCollege of Public Health, Institute of Health Policy and Management, National Taiwan University, Taipei, Taiwan.
Shio-Jean LinGenetic Counseling Center, Chi Mei Medical Center, Tainan, Taiwan.
Meng-Chih LeeDepartment of Family Medicine, Taichung Hospital, Taichung, Taiwan.
Bih-Ching ShuDepartment of Nursing and Institute of Allied Health Sciences, National Cheng Kung University, No. 1 Da-Hsueh Rd., Tainan, 701, Taiwan. forweylung@gmail.com.ORCID 0000-0001-7697-1493

Funding

Bureau of Health Promotion DOH94-HP-1802Bureau of Health Promotion DOH95-HP-1802Bureau of Health Promotion DOH96-HP-1702Bureau of Health Promotion DOH99-HP-1702
6 · The paper itself

Abstract

Objective Previous studies have shown inconsistent results with regard to the association between advanced parental age and autism spectrum disorder (ASD). The sociodemographic status of parents has been found to be associated with children with ASD, however. Therefore, a pathway analysis was undertaken of the roles of maternal age and education in ASD diagnosis and community screening, in a national birth cohort database, using a propensity score matching (PSM) method. Method The 6- and 66-month Taiwan Birth Cohort Study dataset was used (N = 20,095). The PSM exact matching method was used to select 1700 families (ratio of 1:4 between ASD diagnosis and control) from the Taiwan Birth Cohort Study dataset. Results (1) The results from the complete dataset and the PSM exact matching dataset both show that the risk of a child being diagnosed with ASD was increased by the mother being over 40 years old. (2) Although more children of mothers with lower-than-average education were positive on screening, more children of mothers with higher-than-average education were also diagnosed with ASD. Conclusions for Practice Advanced maternal age had a higher association with the diagnosis of ASD, and maternal educational disparity was found between ASD clinical diagnosis and community screening. Community and primary medical care services should pay more attention to children of parents with lower education during ASD screening to prevent delayed diagnosis.

Indexed as

Maternal AgeAdultAutism Spectrum DisorderChildChild, PreschoolCohort StudiesFemaleHumansMaleMothersPropensity ScoreTaiwanM-CHATPropensity score matchingTaiwan Birth Cohort Study

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.