Evidence map›Paper›PMID 29411230›Full record

ArticleJournal of clinical immunology2018

Hematologic Manifestations of Deficiency of Adenosine Deaminase 2 (DADA2) and Response to Tumor Necrosis Factor Inhibition in DADA2-Associated Bone Marrow Failure.

Thomas F Michniacki, Mark Hannibal, Charles W Ross, David G Frame, Adam S DuVall, Rami Khoriaty, Mark T Vander Lugt, Kelly J Walkovich

Abstract readCase ReportsLetter
PubMed Publisher
In one paragraph

Article in Journal of clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Mimics and challenging presentations of DADA2.Clinical and experimental immunology · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. A Cohort Study on Deficiency of ADA2 from China.Journal of clinical immunology · 2023
    Article
  11. Review
  12. Article
  13. Review
  14. Understanding neutropenia secondary to intrinsic or iatrogenic immune dysregulation.Hematology. American Society of Hematology. Education Program · 2021
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thomas F MichniackiPediatrics and Communicable Diseases, Pediatric Hematology/Oncology, University of Michigan, 1500 E. Medical Center Drive, D4202 Medical Professional Building, Ann Arbor, MI, 48109, USA. tmich@med.umich.edu.
Mark HannibalPediatrics - Genetics, University of Michigan, Ann Arbor, MI, USA.
Charles W RossDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
David G FrameDepartment of Pharmacy, University of Michigan, Ann Arbor, MI, USA.
Adam S DuVallPediatric Hematology/Oncology, Oregon Health Sciences University, Portland, OR, USA.
Rami KhoriatyDepartment of Internal Medicine, Hematology/Oncology, University of Michigan, Ann Arbor, MI, USA.
Mark T Vander LugtPediatrics and Communicable Diseases, Pediatric Hematology/Oncology, University of Michigan, 1500 E. Medical Center Drive, D4202 Medical Professional Building, Ann Arbor, MI, 48109, USA.
Kelly J WalkovichPediatrics and Communicable Diseases, Pediatric Hematology/Oncology, University of Michigan, 1500 E. Medical Center Drive, D4202 Medical Professional Building, Ann Arbor, MI, 48109, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenosine DeaminaseAnemia, AplasticBiomarkersBiopsyBone MarrowBone Marrow DiseasesBone Marrow Failure DisordersHematologic TestsHemoglobinuria, ParoxysmalHumansImmunosuppressive AgentsIntercellular Signaling Peptides and ProteinsMaleMiddle AgedSevere Combined ImmunodeficiencySymptom AssessmentADA2 protein, humanAdenosine DeaminaseBiomarkersImmunosuppressive AgentsIntercellular Signaling Peptides and ProteinsTumor Necrosis Factor-alpha

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.