Evidence map›Paper›PMID 29411202›Full record

ArticleJournal of industrial microbiology & biotechnology2018

Regulatory and biosynthetic effects of the bkd gene clusters on the production of daptomycin and its analogs A21978C

Shuai Luo, Xin-Ai Chen, Xu-Ming Mao, Yong-Quan Li

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of industrial microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. A new paradigm for the regulation of A40926B0 biosynthesis.Synthetic and systems biotechnology · 2025
    Article
  2. Article
  3. Article
  4. m4C DNA methylation regulates biosynthesis of daptomycin inSynthetic and systems biotechnology · 2022
    Article
  5. Article
  6. Article
  7. Improving the Yield and Quality of Daptomycin inFrontiers in microbiology · 2022
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shuai LuoInstitute of Pharmaceutical Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Xin-Ai ChenInstitute of Pharmaceutical Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Xu-Ming MaoInstitute of Pharmaceutical Biotechnology, Zhejiang University, Hangzhou, 310058, China. xmmao@zju.edu.cn.
Yong-Quan LiInstitute of Pharmaceutical Biotechnology, Zhejiang University, Hangzhou, 310058, China. lyq@zju.edu.cn.
Zhejiang University · CN

Funding

National Natural Science Foundation of China 31520103901National Natural Science Foundation of China 31571284National Natural Science Foundation of China 31730002National Natural Science Foundation of China 31770071
6 · The paper itself

Abstract

Daptomycin is a cyclic lipopeptide antibiotic produced by Streptomyces roseosporus in an acidic peptide complex A21978C. In this complex, A21978C

Indexed as

Gene Expression Regulation, BacterialMultigene FamilyMutation3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)AllelesAmino Acids, Branched-ChainAnti-Bacterial AgentsBacterial ProteinsDaptomycinDeoxyribonuclease IEscherichia coliGene Expression Regulation, EnzymologicGenes, ReporterGreen Fluorescent ProteinsIntercellular Signaling Peptides and ProteinsPeptides3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)A 21978C1Amino Acids, Branched-ChainAnti-Bacterial AgentsBacterial ProteinsDaptomycinDeoxyribonuclease IGreen Fluorescent ProteinsIntercellular Signaling Peptides and ProteinsPeptidesBranched-chain fatty acidDaptomycinStreptomycesTranscriptional regulationα-Keto acid dehydrogenase

Identifiers

PMID29411202
OpenAlexW2793344216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.