Trial reportOral and maxillofacial surgery2018
To assess the efficacy of socket plug technique using platelet rich fibrin with or without the use of bone substitute in alveolar ridge preservation: a prospective randomised controlled study.
Trial report in Oral and maxillofacial surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 11 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Use of cells and/or biologics combined with scaffolds in alveolar bone augmentation for implant site development.Journal of periodontology · 2026Pooled it
- The efficacy of platelet-rich fibrin in alveolar ridge preservation: a systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2026Pooled it
- Component network meta-analysis of scaffold materials, platelet-rich fibrin and barrier membranes for alveolar ridge preservation.Frontiers in oral health · 2026Pooled it
- Analgesic effects of platelet-rich fibrin (PRF): A systematic review.Periodontology 2000 · 2025Pooled it
- The histological and radiological evaluation of autologous peripheral venous blood concentrates in socket preservation: a systematic review and meta-analysis.Frontiers in dental medicine · 2025Pooled it
- Efficacy of biologics for alveolar ridge preservation/reconstruction and implant site development: An American Academy of Periodontology best evidence systematic review.Journal of periodontology · 2022Pooled it
- Regenerative Potential of Platelet Rich Fibrin (PRF) in Socket Preservation in Comparison with Conventional Treatment Modalities: A Systematic Review and Meta-Analysis.Tissue engineering and regenerative medicine · 2022Pooled it
- Dimensional and histomorphometric evaluation of biomaterials used for alveolar ridge preservation: a systematic review and network meta-analysis.Clinical oral investigations · 2022Pooled it
- Efficacy of platelet-rich fibrin in promoting the healing of extraction sockets: a systematic review.International journal of implant dentistry · 2021Pooled it
- Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development.The Cochrane database of systematic reviews · 2021Pooled it
- Socket seal surgery techniques in the esthetic zone: a systematic review with meta-analysis and trial sequential analysis of randomized clinical trials.International journal of implant dentistry · 2021Pooled it
- Clinical and radiographic efficacy of photobiomodulation, platelet-rich fibrin, and their combination for socket preservation: a randomized clinical trial.BMC oral health · 2026Trial
- Efficacy of Platelet-Rich Fibrin in Preserving Alveolar Ridge Volume and Reducing Postoperative Pain in Site Preservation of Post-Extracted Sockets.Medicina (Kaunas, Lithuania) · 2024Trial
- Alveolar ridge preservation in post-extraction sockets using concentrated growth factors: a split-mouth, randomized, controlled clinical trial.Frontiers in endocrinology · 2023Trial
- New technologies in oral reconstructive medicine: Consensus report of the AAP/OF/SEPA Workshop.Journal of periodontology · 2026Article
- Definite Implant Position as Novel Readout for Effectiveness of Ridge Preservation Indicates to Beneficial Effect of Combined Treatment with Platelet-Rich Fibrin (PRF) and Xenogenic Biomaterial in Bone Regeneration.Bioengineering (Basel, Switzerland) · 2026Article
- Effectiveness of Autologous Plasma Rich in Growth Factors on Healing of Extraction Socket-A Systematic Review.Journal of clinical medicine · 2026Review
- Covered Socket Residuum (CSR) in Former Third Molar Sockets Despite Platelet-Rich Fibrin: A Prospective Randomized Controlled Split-Mouth Clinical Study.Bioengineering (Basel, Switzerland) · 2025Article
- Development of Semi-Automated Image-Based Analysis Tool for CBCT Evaluation of Alveolar Ridge Changes After Tooth Extraction.Bioengineering (Basel, Switzerland) · 2025Article
- Introduction of a Semi-Quantitative Image-Based Analysis Tool for CBCT-Based Evaluation of Bone Regeneration in Tooth Extraction Sockets.Bioengineering (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe purpose of this study is to evaluate the efficacy of Platelet Rich Fibrin (PRF) as a socket plug with or without use of Plaster of Paris (POP) as bone substitute to preserve the alveolar ridge post-extraction. MATERIAL AND
methodsA prospective randomised single blind controlled study, was conducted for 18 months from November 2014 to May 2016 on 48 patients requiring extraction. All teeth were extracted atraumatically using periotomes and luxators without raising mucoperiosteal flap. Sockets were randomly allotted to groups A, B and C. Group A sockets were chosen as control, where figure of eight suture was placed. In group B sockets, PRF obtained by centrifugation was used as a socket plug and stabilised with figure of eight suture. Group C sockets were filled with POP and then covered with PRF. The socket was then closed with a figure of eight suture. Patients were informed of need for 6 months follow-up.
resultsNinety sockets in 48 patients were subjected to our study. We found that results in the sockets where we have grafted POP showed better ridge preservation and post-operative comfort even though the difference in ridge resorption between the three groups was not statistically significant. Powered by Editorial Manager® and ProduXion Manager® from the Aries Systems Corporation.
conclusionAtraumatic extraction may minimise the post-operative pain and discomfort to patient as well as the post-extraction alveolar height and width changes. The use of PRF and/or bone substitute even though clinically contributes to better post-operative healing and minimal loss of alveolar width and height, the values were not statistically significant.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.