Evidence map›Paper›PMID 29411147›Full record

ReviewCurrent neurology and neuroscience reports2018

Atrial Fibrillation for the Neurologist: Preventing both Ischemic and Hemorrhagic Strokes.

Elif Gokcal, Marco Pasi, Marc Fisher, M Edip Gurol

Open access · hybridAbstract readReview
In one paragraph

Review in Current neurology and neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. A practical approach to the management of cerebral amyloid angiopathy.International journal of stroke : official journal of the International Stroke Society · 2021
    Review
  6. Article
  7. Article
  8. Targeting NLRP3 Inflammasome in the Treatment of CNS Diseases.Frontiers in molecular neuroscience · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Elif GokcalDepartment of Neurology, Bezmialem University, Istanbul, Turkey.
Marco PasiDepartment of Neurology, Hemorrhagic Stroke Research Program, Massachusetts General Hospital, 175 Cambridge Street, Suite 300, Boston, MA, 02114, USA.
Marc FisherDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
M Edip GurolDepartment of Neurology, Hemorrhagic Stroke Research Program, Massachusetts General Hospital, 175 Cambridge Street, Suite 300, Boston, MA, 02114, USA. edip@mail.harvard.edu.
Massachusetts General Hospital · USBeth Israel Deaconess Medical Center · USBezmiâlem Vakıf Üniversitesi · TR

Funding

Molecular Neuroimaging of Disease Mechanisms in Cerebral Amyloid AngiopathyK23NS083711 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI GUROL, MAHMUT EDIP · 2014 to 2018
$988k
NINDS NIH HHS K23 NS083711
6 · The paper itself

Abstract

purpose of reviewThis review aims to help neurologists managing atrial fibrillation (AF) patients who had an ischemic stroke and/or with intracranial hemorrhage (ICH) markers, therefore at high embolic/hemorrhagic risks. RECENT

findingsImplantable loop recorders have substantially improved the accuracy of AF detection. Recent research yielded a set of powerful neuroimaging markers that can stratify ICH risk. Direct oral anticoagulants (DOAC) are easier to use with a lower ICH risk than warfarin in a general AF population. Finally, the FDA-approved left atrial appendage closure (LAAC) with the WATCHMAN device provides an option without the need for life-long anticoagulation. In this review, we introduce the concept of preventing both ischemic and hemorrhagic strokes in AF patients through accurate AF diagnosis and stratification of both embolic and ICH risks. LAAC can be considered in patients at higher hemorrhagic risks while warfarin/DOAC use should be individualized in the majority of AF patients at a low risk of bleeding.

Indexed as

AnticoagulantsAtrial AppendageAtrial FibrillationEmbolismHumansIntracranial HemorrhagesIschemiaNeurologistsStrokeAnticoagulantsAtrial fibrillationIntracerebral hemorrhageIschemic strokeLeft atrial appendage closure

Identifiers

PMID29411147
PMCPMC5801393
OpenAlexW2791556060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.