ArticleEuropean journal of applied physiology2018
Changes in central and peripheral neuromuscular fatigue indices after concentric versus eccentric contractions of the knee extensors.
Article in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06953258 (Effects of Home-Based Eccentric Training at Long Muscle Length on Functional Capacity and Neuromechanical Function in Healthy Older Adults), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Home-Based Eccentric Training at Long Muscle Length on Functional Capacity and Neuromechanical Function in Healthy Older Adults
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of eccentric phase tempo on acute neuromechanical responses and short-term post-exercise recovery in healthy trained and recreationally active adults: a systematic review.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion: A Randomized Controlled Trial.International journal of environmental research and public health · 2026Trial
- Neuromuscular fatigue differences between prepubertal boys and men after maximal concentric versus eccentric isokinetic knee extensions.European journal of applied physiology · 2026Trial
- Fatigue Induced by Walking Uphill and Downhill Similarly Disrupts Postural Balance but Their Disruptive Factors Differ.Brain sciences · 2026Article
- Effects of Performing Eccentric Contractions to Failure After Concentric Muscle Failure in Resistance Training Sessions: Protocol for a Within-Participant Randomized Trial.JMIR research protocols · 2026Article
- Supine Bridge Exercise for Low Back Pain: A Fascial Approach for Movement Impairment Syndromes (Part II).Cureus · 2025Review
- Cell-free DNA kinetics in response to muscle-damaging exercise: A drop jump study.Experimental physiology · 2024Article
- Effects of Unilateral Eccentric versus Concentric Training of Nonimmobilized Arm during Immobilization.Medicine and science in sports and exercise · 2023Article
- Less fatiguability in eccentric than concentric repetitive maximal muscle contractions.European journal of applied physiology · 2023Article
- Acute adaptation of central and peripheral motor unit features to exercise-induced fatigue differs with concentric and eccentric loading.Experimental physiology · 2023Article
- Resistance exercise with different workloads have distinct effects on cellular respiration of peripheral blood mononuclear cells.Physiological reports · 2022Article
- Changes in biceps brachii muscle hardness assessed by a push-in meter and strain elastography after eccentric versus concentric contractions.Scientific reports · 2022Article
- The Effects of High-Intensity Functional Training on Cognition in Older Adults with Cognitive Impairment: A Systematic Review.Healthcare (Basel, Switzerland) · 2022Review
- Toward Soft Wearable Strain Sensors for Muscle Activity Monitoring.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2022Article
- Neuromuscular responses to isometric, concentric and eccentric contractions of the knee extensors at the same torque-time integral.European journal of applied physiology · 2022Article
- Muscle Shear Elastic Modulus Provides an Indication of the Protection Conferred by the Repeated Bout Effect.Frontiers in physiology · 2022Article
- Downhill running impairs peripheral but not central neuromuscular indices in elbow flexor muscles.Sports medicine and health science · 2021Article
- Eccentric Resistance Training in Youth: A Survey of Perceptions and Current Practices by Strength and Conditioning Coaches.Journal of functional morphology and kinesiology · 2021Article
- Moving forward with backward pedaling: a review on eccentric cycling.European journal of applied physiology · 2021Review
- Recovery From Eccentric Squat Exercise in Resistance-Trained Young and Master Athletes With Similar Maximum Strength: Combining Cold Water Immersion and Compression.Frontiers in physiology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo better understand neuromuscular characteristics of eccentric exercise-induced muscle damage, this study compared between concentric (CONC) and eccentric (ECC) exercises of knee extensor muscles, and the first (ECC1) and second bouts of the eccentric exercise (ECC2) for central and peripheral parameters associated with neuromuscular fatigue.
methodsTwelve young men performed three exercise bouts separated by at least 1 week between CONC and ECC1, and 2 weeks between ECC1 and ECC2. In each exercise, maximal voluntary concentric or eccentric contractions of the knee extensors were performed until a reduction in maximal voluntary isometric contraction (MVC) torque of at least 40% MVC was achieved immediately post-exercise. MVC torque, central (voluntary activation and normalised electromyographic activity), and peripheral neuromuscular indices (evoked torque and M-wave amplitude), and muscle soreness were assessed before (PRE), immediately after (POST), 1 h (1H), and 1-4 days after exercise (D1, D2, D3, and D4).
resultsMVC torque decreased at only POST for CONC (- 52.8%), but remained below the baseline at POST (- 48.6%), 1H (- 34.1%), and D1-D4 (- 34.1 to - 18.2%) after ECC1, and at POST (- 45.2%), 1H (- 24.4%) and D1 (- 13.4%) after ECC2 (p < 0.05). Voluntary activation decreased immediately after ECC1 (- 21.6%) and ECC2 (- 21.1%), but not after CONC. Electrically evoked torques decreased similarly at POST and 1H for the three conditions, but remained below the baseline at D1 only post-ECC1.
conclusionThese results showed that both central and peripheral factors contributed to the MVC decrease after ECC1 and ECC2, but the decrease was mainly due to peripheral factors after CONC.
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Registered trials
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