Evidence map›Paper›PMID 29411048›Full record

SynthesisEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2019

Comparison of analgesic interventions for traumatic rib fractures: a systematic review and meta-analysis.

Jesse Peek, Diederik P J Smeeing, Falco Hietbrink, Roderick M Houwert, Marije Marsman, Mirjam B de Jong

2 registry-linked trialsAbstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04745520 naterminatednot on this mapstarted 2021, after this paper: background citation

Comparison of Rib Fixation with Medical Analgesia in Patients with Uncomplicated Rib Fractures on Pain Control: a Multi-center Randomized Clinical Trial

TypeinterventionalSponsorBenoît BédatRan2021 to 2024Enrolled102ConditionsRib FracturesArmsRib fixation, Analgesia
NCT04937933 phase4completednot on this map

The Effect of Coolant Spray on Rib Fracture Pain of Geriatric Blunt Thoracic Trauma Patients: a Randomized Controlled Trial

TypeinterventionalSponsorAtaturk UniversityRan2019 to 2020Enrolled101ConditionsThorax, Fracture, Pain, Thorax, Thoracic, Spine, With Radicular and Visceral PainArmsCoolant spray (Cryos ®Spray, Phyto Performance, Italy), Saline solution
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Thoracic injuries in elderly trauma patients epidemiology, injury characteristics, in-hospital care and outcome.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. A deep learning-based approach to automated rib fracture detection and CWIS classification.International journal of computer assisted radiology and surgery · 2025
    Article
  9. Article
  10. Regional anaesthesia techniques for management of severe chest wall trauma: a major trauma centre retrospective observational study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Observational
  11. Article
  12. Article
  13. Article
  14. Review
  15. Analgesia for rib fractures: a narrative review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Review
  16. Review
  17. The Role of Regional Anaesthesia and Acute Pain Services in Value-Based Healthcare.Turkish journal of anaesthesiology and reanimation · 2023
    Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jesse PeekDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. j.peek1994@gmail.com.ORCID http://orcid.org/0000-0003-0667-4076
Diederik P J SmeeingDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Falco HietbrinkDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Roderick M HouwertDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Marije MarsmanDepartment of Anesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Mirjam B de JongDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMany studies report on outcomes of analgesic therapy for (suspected) traumatic rib fractures. However, the literature is inconclusive and diverse regarding the management of pain and its effect on pain relief and associated complications. This systematic review and meta-analysis summarizes and compares reduction of pain for the different treatment modalities and as secondary outcome mortality during hospitalization, length of mechanical ventilation, length of hospital stay, length of intensive care unit stay (ICU) and complications such as respiratory, cardiovascular, and/or analgesia-related complications, for four different types of analgesic therapy: epidural analgesia, intravenous analgesia, paravertebral blocks and intercostal blocks.

methodsPubMed, EMBASE and CENTRAL databases were searched to identify comparative studies investigating epidural, intravenous, paravertebral and intercostal interventions for traumatic rib fractures, without restriction for study type. The search strategy included keywords and MeSH or Emtree terms relating blunt chest trauma (including rib fractures), analgesic interventions, pain management and complications.

resultsA total of 19 papers met our inclusion criteria and were finally included in this systematic review. Significant differences were found in favor of epidural analgesia for the reduction of pain. No significant differences were observed between epidural analgesia, intravenous analgesia, paravertebral blocks and intercostal blocks, for the secondary outcomes.

conclusionsResults of this study show that epidural analgesia provides better pain relief than the other modalities. No differences were observed for secondary endpoints like length of ICU stay, length of mechanical ventilation or pulmonary complications. However, the quality of the available evidence is low, and therefore, preclude strong recommendations.

Indexed as

Administration, IntravenousAdolescentAdultAgedAnalgesia, EpiduralAnalgesicsCritical CareEpidemiologic MethodsHumansLength of StayMiddle AgedMusculoskeletal PainNerve BlockPain MeasurementRib FracturesYoung AdultAnalgesicsAnalgesiaAnesthesiaHospitalizationMortalityPain ManagementRib Fractures

Identifiers

PMID29411048
PMCPMC6689037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.