Evidence map›Paper›PMID 29410961›Full record

ArticleBioMed research international2017

The Diagnostic Roles of Cytokines in Hepatobiliary Cancers.

Yavuz Savas Koca, Mahmut Bulbul, Ibrahim Barut

Registry-linked trialAbstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05743530 (Effect of Perioperative Neurostimulation in Patients Undergoing Whipple Operation), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05743530 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Perioperative Neurostimulation in Patients Undergoing Whipple Operation (Pancreaticoduodenectomy) on Acute Postsurgical Inflammatory Response [ENSWAPI-trial]

TypeinterventionalSponsorMedical University of GrazRan2023 to 2025Enrolled90ConditionsPancreaticoduodenectomyArmsTENS - transcutaneous electrical nerve stimulation, Placebo
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yavuz Savas KocaDepartment of General Surgery, School of Medicine, Suleyman Demirel University, Isparta, Turkey.ORCID 0000-0001-6543-3622
Mahmut BulbulDepartment of General Surgery, School of Medicine, Suleyman Demirel University, Isparta, Turkey.
Ibrahim BarutHPB Surgery Unit, Department of General Surgery, School of Medicine, Suleyman Demirel University, Isparta, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to investigate the role of several cytokines including IL-2, IL-6, IL-8, IL-10, and TNF- MATERIALS AND

methodsThe prospective study was performed between October 2007 and September 2014. The study included 226 patients who were divided into 5 groups depending on their postoperative and histopathologic diagnosis: Control group included 30 healthy volunteers. Hepatocellular cancer (HCC) group included 24 patients diagnosed with HCC. Gallbladder cancer (GBC) group included 36 patients diagnosed with GBC. Cholangiocellular carcinoma group included 64 patients diagnosed with cholangiocellular carcinoma. Pancreatic cancer group included 72 patients diagnosed with pancreatic cancer. Serum levels of IL-2, IL-6, IL-8, IL-10, and TNF-

resultsSerum TNF-

conclusionWe suggest that cytokines can be used as useful markers in the diagnosis of HPB cancers.

Indexed as

AdultAgedAged, 80 and overBiliary Tract NeoplasmsCase-Control StudiesCytokinesFemaleHumansLiver NeoplasmsMaleMiddle AgedCytokines

Identifiers

PMID29410961
PMCPMC5749214

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.