Evidence map›Paper›PMID 29410606›Full record

Trial reportJournal of the International Society of Sports Nutrition2018

Effects of lemon verbena extract (Recoverben®) supplementation on muscle strength and recovery after exhaustive exercise: a randomized, placebo-controlled trial.

Sybille Buchwald-Werner, Ioanna Naka, Manfred Wilhelm, Elivra Schütz, Christiane Schoen, Claudia Reule

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02923102 (Effects of Recoverben® on Recovery After Exhaustive Exercise in Healthy People - a Randomized, Double-blind, Placebo-controlled Study With Parallel Design), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02923102 nacompletednot on this map

Effects of Recoverben® on Recovery After Exhaustive Exercise in Healthy People - a Randomized, Double-blind, Placebo-controlled Study With Parallel Design

TypeinterventionalSponsorVital Solutions GmbHRan2016 to 2017Enrolled40ConditionsHealthy Volunteers, Muscle Fatigue, Muscle SorenessArmsAloysia citriodora extract, Maltodextrin
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Effect ofNutrients · 2026
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  14. Exercise Training andPlants (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sybille Buchwald-WernerVital Solutions GmbH, Hausingerstrasse 6, 40764 Langenfeld, Germany.ORCID 0000-0002-0462-6620
Ioanna NakaVital Solutions GmbH, Hausingerstrasse 6, 40764 Langenfeld, Germany.
Manfred Wilhelm2Ulm University of Applied Sciences, Albert-Einstein-Allee 55, 89081 Ulm, Germany.
Elivra SchützBioTeSys GmbH, Schelztorstrasse 54-56, D-73728 Esslingen, Germany.
Christiane SchoenBioTeSys GmbH, Schelztorstrasse 54-56, D-73728 Esslingen, Germany.
Claudia ReuleBioTeSys GmbH, Schelztorstrasse 54-56, D-73728 Esslingen, Germany.
BioTeSys (Germany) · DEVITA (Germany) · DETechnische Hochschule Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExhaustive exercise causes muscle damage accompanied by oxidative stress and inflammation leading to muscle fatigue and muscle soreness. Lemon verbena leaves, commonly used as tea and refreshing beverage, demonstrated antioxidant and anti-inflammatory properties. The aim of this study was to investigate the effects of a proprietary lemon verbena extract (Recoverben®) on muscle strength and recovery after exhaustive exercise in comparison to a placebo product.

methodsThe study was performed as a randomized, placebo-controlled, double-blind study with parallel design. Forty-four healthy males and females, which were 22-50 years old and active in sports, were randomized to 400 mg lemon verbena extract once daily or placebo. The 15 days intervention was divided into 10 days supplementation prior to the exhaustive exercise day (intensive jump-protocol), one day during the test and four days after. Muscle strength (MVC), muscle damage (CK), oxidative stress (GPx), inflammation (IL6) and volunteer-reported muscle soreness intensity were assessed pre and post exercise.

resultsParticipants in the lemon verbena group benefited from less muscle damage as well as faster and full recovery. Compared to placebo, lemon verbena extract receiving participants had significantly less exercise-related loss of muscle strength (

conclusionLemon verbena extract (Recoverben®) has been shown to be a safe and well-tolerated natural sports ingredient, by reducing muscle damage after exhaustive exercise.

trial registrationThe trial was registered in the clinical trials registry (clinical trial.gov NCT02923102). Registered 28 September 2016.

Indexed as

Dietary SupplementsExerciseAdultCreatine KinaseFemaleHumansInflammationInterleukin-6MaleMiddle AgedMuscle, SkeletalMuscle StrengthMyalgiaOxidative StressPlant ExtractsSports Nutritional Physiological PhenomenaCreatine KinaseIL6 protein, humanInterleukin-6Plant ExtractsAloysia citriodoraeiMDExhaustive exerciseGlutathione peroxidasesLemon verbenaMuscle sorenessMuscle strengthRecoverben®RecoverySports nutrition

Identifiers

PMID29410606
PMCPMC5781260
OpenAlexW2784583400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.