Evidence map›Paper›PMID 29410548›Full record

ArticleBone marrow transplantation2018

Analysis of the Spanish CCR5-∆32 inventory of cord blood units: lower cell counts in homozygous donors.

Emma Enrich, Francisco Vidal, Francisco Sánchez-Gordo, Juan M Gómez-Zumaquero, Antonio Balas, Francesc Rudilla, Luisa Barea, Ana Castro, Luis Larrea, Miguel A Perez-Vaquero and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Emma EnrichBanc de Sang i Teixits, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain.
Francisco VidalBanc de Sang i Teixits, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain.
Francisco Sánchez-GordoBanco de Cordón de Andalucía, Centro Transfusión de Málaga, Málaga, Spain.
Juan M Gómez-ZumaqueroBanco de Cordón de Andalucía, Centro Transfusión de Málaga, Málaga, Spain.
Antonio BalasBanco de Cordón de Madrid, Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain.
Francesc RudillaBanc de Sang i Teixits, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain.
Luisa BareaBanco de Cordón de Madrid, Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain.
Ana CastroBanco de Cordón de Galicia, Axencia Galega de Doazón de Sangue e Tecidos, Santiago de Compostela, Spain.
Luis LarreaBanco de Cordón de Valencia, Centro de Transfusión de la Comunidad Valenciana, Valencia, Spain.
Miguel A Perez-VaqueroBanco de Cordón del País Vasco, Centro Vasco de Transfusión y Tejidos Humanos, Galdakao, Spain.
Isidro PratBanco de Cordón de Andalucía, Centro Transfusión de Málaga, Málaga, Spain.
Sergio QuerolBanc de Sang i Teixits, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain. squerol@bst.cat.
Gregorio GarridoOrganización Nacional de Trasplantes (ONT), Madrid, Spain.
Rafael MatesanzOrganización Nacional de Trasplantes (ONT), Madrid, Spain.
Enric CarrerasSpanish Bone Marrow Donor Registry (REDMO), Barcelona, Spain.
Rafael F DuarteHospital Universitario Puerta de Hierro Majadahonda, Universidad Autónoma de Madrid, Majadahonda, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The possibility to use CCR5-∆32 umbilical cord blood to cure HIV infection in patients in need of a hematopoietic transplant has been suggested. The less stringent HLA compatibility needed in this type of transplant facilitates the search of a suitable donor having the CCR5-∆32 mutation. To achieve an inventory of CCR5-∆32 cord blood units, the 20,236 best cell quality units of the Spanish Registry were genotyped. Furthermore, their CD34

Indexed as

Cord Blood Stem Cell TransplantationFemaleGenotypeHomozygoteHumansMaleReceptors, CCR5Tissue DonorsCCR5 protein, humanReceptors, CCR5

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.