ArticleNature communications2018
Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 50 citations in OpenAlex.
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- Collagen IV biosynthesis: Intracellular choreography of post-translational modifications.Matrix biology : journal of the International Society for Matrix Biology · 2025Review
- Enzymatic craftsmanship in collagen glycosylation.Nature communications · 2025Article
- Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis.Nature communications · 2025Article
- The Crystal Structure ofBiochemistry · 2025Article
- Structure of an FeActa crystallographica. Section F, Structural biology communications · 2025Article
- Cloning, expression, and characterization of collagen galactosyltransferases from human, sponge, and sea walnut.Protein expression and purification · 2025Article
- Lysyl hydroxylase 2 glucosylates collagen VI to drive lung cancer progression.The Journal of clinical investigation · 2025Article
- Iron and Cancer.Advances in experimental medicine and biology · 2025Review
- An Active Site Tyr Residue Guides the Regioselectivity of Lysine Hydroxylation by Nonheme Iron Lysine-4-hydroxylase Enzymes through Proton-Coupled Electron Transfer.Journal of the American Chemical Society · 2024Article
- Understanding the matrix: collagen modifications in tumors and their implications for immunotherapy.Journal of translational medicine · 2024Review
- Glycosylation Modulates the Structure and Functions of Collagen: A Review.Molecules (Basel, Switzerland) · 2024Review
- Modeling of Protein Complexes.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Super-enhanced MARCO variant drives triple-negative breast cancer progression.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Superenhancer drives a tumor-specific splicing variant of MARCO to promote triple-negative breast cancer progression.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The Astounding World of Glycans from Giant Viruses.Chemical reviews · 2022Review
- Comparative genomic and biochemical analyses identify a collagen galactosylhydroxylysyl glucosyltransferase from Acanthamoeba polyphaga mimivirus.Scientific reports · 2022Article
- A FeFrontiers in molecular biosciences · 2022Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
18 authors at 4 institutions in 2 countries.
Hou-Fu GuoDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.ORCID http://orcid.org/0000-0002-3659-9399
Chi-Lin TsaiDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.ORCID http://orcid.org/0000-0002-0365-2405
Masahiko TerajimaNorth Carolina Oral Health Institute, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.ORCID http://orcid.org/0000-0002-1502-7930
Xiaochao TanDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Priyam BanerjeeDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Mitchell D MillerDepartment of Biosciences, Rice University, Houston, TX, 77251, USA.ORCID http://orcid.org/0000-0003-1626-4943
Xin LiuDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Jiang YuDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Jovita ByemerwaDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Sarah AlvaradoDepartment of Biosciences, Rice University, Houston, TX, 77251, USA.
Tamer S KaoudDivision of Medicinal Chemistry, Targeted Therapeutic Drug Discovery and Development Program, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA.
Kevin N DalbyDivision of Medicinal Chemistry, Targeted Therapeutic Drug Discovery and Development Program, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA.
Neus Bota-RabassedasDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Yulong ChenDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Mitsuo YamauchiNorth Carolina Oral Health Institute, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
John A TainerDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. jtainer@mdanderson.org.ORCID http://orcid.org/0000-0003-1659-2429
George N PhillipsDepartment of Biosciences, Rice University, Houston, TX, 77251, USA. georgep@rice.edu.
Jonathan M KurieDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. jkurie@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USRice University · USAustin College · USUniversity of North Carolina at Chapel Hill · US
Funding
UNIVERSITY OF TEXAS--SPORE IN LUNG CANCERP50CA070907 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI GIBBONS, DON LYNN · 1996 to 2024
$57.4MUser Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6MHOUSTON AREA MOLECULAR BIOPHYSICS TRAINING PROGRAMT32GM008280 · NIGMS · RICE UNIVERSITY · PI WENSEL, THEODORE G · 1988 to 2023
$8.0MRegulation of Lung Cancer Metastasis by a Procollagen Lysine HydroxylaseR01CA105155 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KURIE, JONATHAN M · 2004 to 2019
$4.0MRegulation of eEF-2K an Energy and Nutrient SensorR01GM123252 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI DALBY, KEVIN N, GHOSE, RANAJEET · 2017 to 2024
$2.7MMechanism and Specificity of MAP KinasesR01GM059802 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI DALBY, KEVIN N · 2001 to 2011
$2.3MMINOS (Macromolecular Insights on Nucleic acids Optimized by Scattering)R01GM105404 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI TAINER, JOHN A. · 2012 to 2015
$2.1MA Pixel Array Detector System for Small Angle X-ray ScatteringS10OD018483 · OD · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI CLASSEN, SCOTT · 2014 to 2014
$998kCollagen Glycosylation, Maturation and MineralizationR21AR060978 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAMAUCHI, MITSUO · 2012 to 2013
$352kNCI NIH HHS P50 CA070907NCI NIH HHS R01 CA105155NIAMS NIH HHS R21 AR060978NIGMS NIH HHS P30 GM124169NIGMS NIH HHS R01 GM059802NIGMS NIH HHS R01 GM105404NIGMS NIH HHS R01 GM123252NIGMS NIH HHS T32 GM008280NIH HHS S10 OD018483
Abstract
Collagen lysyl hydroxylases (LH1-3) are Fe
Indexed as
Protein MultimerizationAmino Acid SequenceAnimalsCatalytic DomainCell Line, TumorCollagenCrystallography, X-RayEnzyme StabilityHumansIronLung NeoplasmsMice, NudeMimiviridaeMutationNeoplasm MetastasisProcollagen-Lysine, 2-Oxoglutarate 5-DioxygenaseCollagenIronProcollagen-Lysine, 2-Oxoglutarate 5-DioxygenaseViral Proteins
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