Evidence map›Paper›PMID 29410180›Full record

Trial reportBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2018

Plerixafor Plus Granulocyte Colony-Stimulating Factor for Patients with Non-Hodgkin Lymphoma and Multiple Myeloma: Long-Term Follow-Up Report.

Ivana N Micallef, Patrick J Stiff, Auayporn P Nademanee, Richard T Maziarz, Mitchell E Horwitz, Edward A Stadtmauer, Jonathan L Kaufman, John M McCarty, Rita Vargo, Peter D Cheverton and 3 more

2 registry-linked trialsOpen access · hybridAbstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00741325 completednot on this map

Long-term Observational Follow-up Study of a Multicenter, Randomized, Double-blind, Placebo-controlled, Comparative Trial of AMD3100 (240µg/kg) Plus G-CSF (10µg/kg) Versus G-CSF (10µg/kg) Plus Placebo to Mobilize and Collect ≥ 5X 10^6 CD34+ Cells/kg in Non-Hodgkin's Lymphoma Patients for Autologous Transplantation

TypeobservationalSponsorGenzyme, a Sanofi CompanyRan2006 to 2011Enrolled178ConditionsNon-Hodgkin's Lymphoma, Autologous TransplantationArmsgranulocyte colony-stimulating factor (G-CSF), plerixafor, Placebo
NCT00741780 completednot on this map

Long-term Observational Follow-up Study of a Multicenter, Randomized, Double-blind, Placebo-controlled, Comparative Trial of AMD3100 (240µg/kg) Plus G-CSF (10µg/kg) Versus G-CSF (10µg/kg) Plus Placebo to Mobilize and Collect ≥ 6X 10^6 CD34+ Cells/kg in Multiple Myeloma Patients for Autologous Transplantation

TypeobservationalSponsorGenzyme, a Sanofi CompanyRan2006 to 2011Enrolled164ConditionsMultiple Myeloma, Autologous TransplantationArmsPlacebo, plerixafor, granulocyte colony-stimulating factor (G-CSF)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Mobilization Strategies in Myeloma Patients Intended for Autologous Hematopoietic Cell Transplantation.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Observational
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 2 countries.

Ivana N MicallefDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
Patrick J StiffDivision of Hematology/Oncology, Loyola University, Chicago, Illinois.
Auayporn P NademaneeCity of Hope Comprehensive Cancer Center, Duarte, California.
Richard T MaziarzKnight Cancer Institute, Oregon Health & Science University, Portland, Oregon.
Mitchell E HorwitzDivision of Hematologic Malignancies and Cellular Therapy, Duke University School of Medicine, Durham, North Carolina.
Edward A StadtmauerDivision of Hematology/Oncology, University of Pennsylvania, Philadelphia, Pennsylvania.
Jonathan L KaufmanDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia.
John M McCartyDepartment of Internal Medicine, Virginia Commonwealth University Massey Cancer Center, Richmond, Virginia.
Rita VargoSanofi, Cambridge, Massachusetts.
Peter D ChevertonSanofi, Cambridge, Massachusetts.
Martin StruijsSanofi, Naarden, The Netherlands.
Brian BolwellTaussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio.
John F DiPersioDivision of Oncology, Washington University School of Medicine, St. Louis, Missouri. Electronic address: jdipersi@wustl.edu.
Sanofi (United States) · USCity of Hope · USCleveland Clinic · USDuke University · USEmory University · USLoyola University Chicago · USMayo Clinic · USOregon Health & Science University · USSanofi (Netherlands) · NLUniversity of Pennsylvania · USVirginia Commonwealth University · USWashington University in St. Louis · US

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SHELLEY L BERGER · 1985 to 2026
$222.3M
Optimizing Hematopoietic Stem Cell Transplantation For The Treatment Of Hematological MalignanciesR35CA210084 · NCI · WASHINGTON UNIVERSITY · PI John F. Dipersio · 2017 to 2026
$7.8M
NCI NIH HHS P30 CA016520NCI NIH HHS R35 CA210084
6 · The paper itself

Abstract

The purpose of this report is to analyze long-term clinical outcomes of patients exposed to plerixafor plus granulocyte colony-stimulating factor (G-CSF) for stem cell mobilization. This was a study of patients with non-Hodgkin lymphoma (NHL; n = 167) and multiple myeloma (MM; n = 163) who were enrolled in the long-term follow-up of 2 pivotal phase III studies (NCT00741325 and NCT00741780) of 240 µg/kg plerixafor plus 10 µg/kg G-CSF, or placebo plus 10 µg/kg G-CSF to mobilize and collect CD34

Indexed as

AdolescentAdultAgedBenzylaminesChildCyclamsGranulocyte Colony-Stimulating FactorHematopoietic Stem Cell MobilizationHematopoietic Stem Cell TransplantationHeterocyclic CompoundsHumansLongitudinal StudiesLymphoma, Non-HodgkinMiddle AgedMultiple MyelomaSurvival AnalysisBenzylaminesCyclamsGranulocyte Colony-Stimulating FactorHeterocyclic CompoundsplerixaforLong-term follow-upMultiple myelomaNon-Hodgkin lymphomaPlerixaforStem cell mobilization

Identifiers

PMID29410180
PMCPMC6091693
OpenAlexW2785352960

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.