ArticleNeuroImage2018
The developing human connectome project: A minimal processing pipeline for neonatal cortical surface reconstruction.
Article in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 301 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
301 citing papers in PubMed, 4 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- The Relationship Between Family History of Depression and Brain Structure and Function: A Systematic Review of Large Cohorts.Biological psychiatry · 2026Pooled it
- Developmental Brain Age Estimation From MRI Data: A Systematic Review of Deep Learning Approaches and Open Datasets.Journal of magnetic resonance imaging : JMRI · 2026Pooled it
- Fetal brain MRI atlases and datasets: A review.NeuroImage · 2024Pooled it
- A systematic review of automated methods to perform white matter tract segmentation.Frontiers in neuroscience · 2024Pooled it
- Postnatal serum IGF-1 levels associate with brain volumes at term in extremely preterm infants.Pediatric research · 2023Trial
- Stable Thalamic Topography Across Perinatal Development: a Diffusion MRI Study.Brain topography · 2026Article
- Population connective field modeling reveals proto-retinotopic visual cortex organization in the prenatal human brain.Science advances · 2026Article
- Frequency-specific gyro-sulcal functional differentiation in preterm neonates: Sulcal dominance and gene expression correlates.Developmental cognitive neuroscience · 2026Article
- Postnatal distress, neonatal cerebellar myelination and neurodevelopmental outcomes at 18 months.Molecular psychiatry · 2026Article
- Motifs of brain cortical folding from birth to adulthood.Nature communications · 2026Article
- Brain structural and functional connectivity converge prenatally but diverge after birth.PLoS biology · 2026Article
- The shifting landscape of brain-wide myelination across the human lifespan.Nature communications · 2026Article
- AI segmentation requires accounting for brain size to maintain performance on developmental MRI cohorts.bioRxiv : the preprint server for biology · 2026Article
- Multiscale brain development across the human lifespan.Communications biology · 2026Review
- Radiofrequency electrical conductivity reveals a distinct dimension of early human brain development.Scientific reports · 2026Article
- FedFound: a federated foundation model for lifespan brain morphological connectome analysis.NPJ digital medicine · 2026Article
- Cortical and white matter myelination proceed in concert during early infancy.Nature communications · 2026Article
- miniMORPH: A Morphometry Pipeline for Low-Field MRI in Infants.Human brain mapping · 2026Article
- Metabolic expenditure, neurodevelopment, and weight gain into early childhood after fetal growth restriction.Scientific reports · 2026Article
- Harmonization in magnetic resonance imaging: A survey of acquisition, image-level, and feature-level methods.Medical image analysis · 2026Review
241 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors at 4 institutions in 2 countries.
Funding
Abstract
The Developing Human Connectome Project (dHCP) seeks to create the first 4-dimensional connectome of early life. Understanding this connectome in detail may provide insights into normal as well as abnormal patterns of brain development. Following established best practices adopted by the WU-MINN Human Connectome Project (HCP), and pioneered by FreeSurfer, the project utilises cortical surface-based processing pipelines. In this paper, we propose a fully automated processing pipeline for the structural Magnetic Resonance Imaging (MRI) of the developing neonatal brain. This proposed pipeline consists of a refined framework for cortical and sub-cortical volume segmentation, cortical surface extraction, and cortical surface inflation, which has been specifically designed to address considerable differences between adult and neonatal brains, as imaged using MRI. Using the proposed pipeline our results demonstrate that images collected from 465 subjects ranging from 28 to 45 weeks post-menstrual age (PMA) can be processed fully automatically; generating cortical surface models that are topologically correct, and correspond well with manual evaluations of tissue boundaries in 85% of cases. Results improve on state-of-the-art neonatal tissue segmentation models and significant errors were found in only 2% of cases, where these corresponded to subjects with high motion. Downstream, these surfaces will enhance comparisons of functional and diffusion MRI datasets, supporting the modelling of emerging patterns of brain connectivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.