Evidence map›Paper›PMID 29409674›Full record

ArticleArthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association2018

An In Vivo Prediction of Anisometry and Strain in Anterior Cruciate Ligament Reconstruction - A Combined Magnetic Resonance and Dual Fluoroscopic Imaging Analysis.

Willem A Kernkamp, Nathan H Varady, Jing-Sheng Li, Tsung-Yuan Tsai, Peter D Asnis, Ewoud R A van Arkel, Rob G H H Nelissen, Thomas J Gill, Samuel K Van de Velde, Guoan Li

Abstract read
In one paragraph

Article in Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. [A study of early graft healing after anterior cruciate ligament reconstruction in over-the-top position].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
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  6. Anterior cruciate ligament bundle insertions vary between ACL-rupture and non-injured knees.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
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  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Willem A KernkampOrthopaedic Bioengineering Laboratory, Newton-Wellesley Hospital/Harvard Medical School, Newton, Massachusetts, U.S.A.; Department of Orthopaedic Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, U.S.A.; Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Nathan H VaradyDepartment of Orthopaedic Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, U.S.A.
Jing-Sheng LiDepartment of Orthopaedic Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, U.S.A.
Tsung-Yuan TsaiOrthopaedic Bioengineering Laboratory, Newton-Wellesley Hospital/Harvard Medical School, Newton, Massachusetts, U.S.A.
Peter D AsnisDepartment of Orthopaedic Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, U.S.A.
Ewoud R A van ArkelFocus Clinic Orthopedic Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
Rob G H H NelissenOrthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Thomas J GillBoston Sports Medicine and Research Institute, Dedham, Massachusetts, U.S.A.
Samuel K Van de VeldeFocus Clinic Orthopedic Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
Guoan LiOrthopaedic Bioengineering Laboratory, Newton-Wellesley Hospital/Harvard Medical School, Newton, Massachusetts, U.S.A.. Electronic address: Gli1@partners.org.
Massachusetts General Hospital · USLeiden University Medical Center · NLMedisch Centrum Haaglanden · NLNewton Wellesley Hospital · USBoston Biomedical Research Institute · US

Funding

In vivo ACL Reconstruction BiomechanicsR01AR055612 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LI, GUOAN · 2008 to 2012
$1.9M
NIAMS NIH HHS R01 AR055612
6 · The paper itself

Abstract

purposeTo evaluate the in vivo anisometry and strain of theoretical anterior cruciate ligament (ACL) grafts in the healthy knee using various socket locations on both the femur and tibia.

methodsEighteen healthy knees were imaged using magnetic resonance imaging and dual fluoroscopic imaging techniques during a step-up and sit-to-stand motion. The anisometry of the medial aspect of the lateral femoral condyle was mapped using 144 theoretical socket positions connected to an anteromedial, central, and posterolateral attachment site on the tibia. The 3-dimensional wrapping paths of each theoretical graft were measured. Comparisons were made between the anatomic, over the top (OTT), and most-isometric (isometric) femoral socket locations, as well as between tibial insertions.

resultsThe area of least anisometry was found in the proximal-distal direction just posterior to the intercondylar notch. The most isometric attachment site was found midway on the Blumensaat line with approximately 2% and 6% strain during the step-up and sit-to-stand motion, respectively. Posterior femoral attachments resulted in decreased graft lengths with increasing flexion angles, whereas anterodistal attachments yielded increased lengths with increasing flexion angles. The anisometry of the anatomic, OTT and isometric grafts varied between tibial insertions (P < .001). The anatomic graft was significantly more anisometric than the OTT and isometric graft at deeper flexion angles (P < .001).

conclusionsAn area of least anisometry was found in the proximal-distal direction just posterior to the intercondylar notch. ACL reconstruction at the isometric and OTT location resulted in nonanatomic graft behavior, which could overconstrain the knee at deeper flexion angles. Tibial location significantly affected graft strains for the anatomic, OTT, and isometric socket location. CLINICAL RELEVANCE: This study improves the knowledge on ACL anisometry and strain and helps surgeons to better understand the consequences of socket positioning during intra-articular ACL reconstruction.

Indexed as

AdolescentAdultAnterior Cruciate LigamentAnterior Cruciate Ligament ReconstructionBiomechanical PhenomenaEpiphysesFemaleFemurFluoroscopyHumansKnee JointMagnetic Resonance ImagingMaleMiddle AgedMultimodal ImagingRange of Motion, Articular

Identifiers

PMID29409674
PMCPMC5889360
OpenAlexW2786281551

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.