Evidence map›Paper›PMID 29409463›Full record

Observational studyBMC geriatrics2018

Overweight or obese BMI is associated with earlier, but not later survival after common acute illnesses.

Hallie C Prescott, Virginia W Chang

Abstract readObservational Study
In one paragraph

Observational study in BMC geriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Diet-induced obesity in mice impairs host defense againstAmerican journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  7. Article
  8. The obesity paradox and diabetes.Eating and weight disorders : EWD · 2021
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hallie C PrescottDepartment of Internal Medicine, Institute for Healthcare Policy & Innovation, University of Michigan, Ann Arbor, MI, USA. hprescot@med.umich.edu.ORCID 0000-0002-8442-6724
Virginia W ChangDepartment of Social and Behavioral Sciences, NYU College of Global Public Health, New York, NY, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
General pathways and personalized risk of morbidity after sepsisK08GM115859 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PRESCOTT, HALLIE CHRISTINE · 2015 to 2018
$776k
American Diabetes Association 7-12-CT-12NIA NIH HHS U01 AG009740NIGMS NIH HHS GM115859NIGMS NIH HHS K08 GM115859
6 · The paper itself

Abstract

backgroundObesity has been associated with improved short-term mortality following common acute illness, but its relationship with longer-term mortality is unknown.

methodsObservational study of U.S. Health and Retirement Study (HRS) participants with federal health insurance (fee-for-service Medicare) coverage, hospitalized with congestive heart failure (N = 4287), pneumonia (N = 4182), or acute myocardial infarction (N = 2001), 1996-2012. Using cox proportional hazards models, we examined the association between overweight or obese BMI (BMI ≥ 25.0 kg/m

resultsPatients were a median of 79 years old (IQR 71-85 years). The majority of patients were overweight or obese: 60.3% hospitalized for heart failure, 51.5% for pneumonia, and 61.6% for acute myocardial infarction. Overweight or obese BMI was associated with lower mortality at 1 year after hospitalization for congestive heart failure, pneumonia, and acute myocardial infarction-with adjusted hazard ratios of 0.68 (95% CI 0.59-0.79), 0.74 (95% CI: 0.64-0.84), and 0.65 (95%CI: 0.53-0.80), respectively. Among participants who lived to one year, however, subsequent survival was similar between patients with normal versus overweight/obese BMI.

conclusionsIn older Americans, overweight or obese BMI was associated with improved survival following hospitalization for congestive heart failure, pneumonia, and acute myocardial infarction. This association, however, is limited to the shorter-term. Conditional on surviving to one year, we did not observe a survival advantage associated with excess weight.

Indexed as

AgedAged, 80 and overBody Mass IndexFemaleHealth SurveysHeart FailureHospitalizationHumansMaleMedicareMyocardial InfarctionObesityOverweightPneumoniaProportional Hazards ModelsRisk Factorsacute myocardial infarctioncongestive heart failurehospitalizationMedicareobesitypneumonia

Identifiers

PMID29409463
PMCPMC5801673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.