Evidence map›Paper›PMID 29409308›Full record

ArticleGut and liver2018

A Prospective Multicenter Study Evaluating Bleeding Risk after Endoscopic Ultrasound-Guided Fine Needle Aspiration in Patients Prescribed Antithrombotic Agents.

Kazumichi Kawakubo, Kei Yane, Kazunori Eto, Hirotoshi Ishiwatari, Nobuyuki Ehira, Shin Haba, Ryusuke Matsumoto, Keisuke Shinada, Hiroaki Yamato, Taiki Kudo and 13 more

Abstract readClinical StudyMulticenter Study
In one paragraph

Article in Gut and liver, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Kazumichi KawakuboDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Kei YaneCenter for Gastroenterology, Teine Keijinkai Hospital, Sapporo, Japan.
Kazunori EtoDepartment of Gastroenterology, Tomakomai City Hospital, Tomakomai, Japan.
Hirotoshi IshiwatariDepartment of Medical Oncology and Hematology, Sapporo Medical University, Sapporo, Japan.
Nobuyuki EhiraDepartment of Gastroenterology, Japanese Red Cross Kitami Hospital, Kitami, Japan.
Shin HabaDepartment of Gastroenterology, NTT East Sapporo Hospital, Sapporo, Japan.
Ryusuke MatsumotoDepartment of Gastroenterology, Obihiro Kosei Hospital, Obihiro, Japan.
Keisuke ShinadaDepartment of Gastroenterology, Keiwakai Ebetsu Hospital, Ebetsu, Japan.
Hiroaki YamatoDepartment of Gastroenterology and Hepatology, Hakodate City Hospital, Hakodate, Japan.
Taiki KudoDepartment of Gastroenterology, Kushiro Rosai Hospital, Kushiro, Japan.
Manabu OnoderaDepartment of Gastroenterology, NTT East Sapporo Hospital, Sapporo, Japan.
Toshinori OkudaDepartment of Gastroenterology, Oji General Hospital, Tomakomai, Japan.
Yoko Taya-AbeDepartment of Gastroenterology, National Hospital Organization Hokkaido Medical Center, Sapporo, Japan.
Shuhei KawahataDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Kimitoshi KuboDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Yoshimasa KubotaDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Masaki KuwataniDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Hiroshi KawakamiDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Akio KatanumaCenter for Gastroenterology, Teine Keijinkai Hospital, Sapporo, Japan.
Michihiro OnoDepartment of Medical Oncology and Hematology, Sapporo Medical University, Sapporo, Japan.
Tsuyoshi HayashiDepartment of Medical Oncology and Hematology, Sapporo Medical University, Sapporo, Japan.
Minoru UebayashiDepartment of Gastroenterology, Japanese Red Cross Kitami Hospital, Kitami, Japan.
Naoya SakamotoDepartment of Gastroenterology and Hepatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsAlthough the risk of bleeding after endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is low, the safety of EUS-FNA in patients prescribed antithrombotic agents is unclear. Therefore, this study evaluated the incidence of bleeding after EUS-FNA in those patients.

methodsBetween September 2012 and September 2015, patients who were prescribed antithrombotic agents underwent EUS-FNA at 13 institutions in Japan were prospectively enrolled in the study. The antithrombotic agents were managed according to the guidelines of the Japanese Gastrointestinal Endoscopy Society. The rate of bleeding events, thromboembolic events and other complications within 2 weeks after EUS-FNA were analyzed.

resultsOf the 2,629 patients who underwent EUS-FNA during the study period, 85 (62 males; median age, 74 years) patients were included in this stduy. Two patients (2.4%; 95% confidence interval [CI], 0.6% to 8.3%) experienced bleeding events. One patient required surgical intervention for hemothorax 5 hours after EUS-FNA, and the other experienced melena 8 days after EUS-FNA and required red blood cell transfusions. No thromboembolic events occurred (0%; 95% CI, 0.0% to 4.4%). Three patients (3.5%; 95% CI, 1.2% to 10.0%) experienced peri-puncture abscess formation.

conclusionsThe rate of bleeding after EUS-FNA in patients prescribed antithrombotic agents might be considerable.

Indexed as

AdultAgedAged, 80 and overEndoscopic Ultrasound-Guided Fine Needle AspirationFemaleFibrinolytic AgentsGastrointestinal HemorrhageHemothoraxHumansMaleMelenaMiddle AgedPrognosisProspective StudiesRisk FactorsFibrinolytic AgentsEndoscopic ultrasound-guided fine needle aspirationFibrinolytic agentsHemorrhage

Identifiers

PMID29409308
PMCPMC5945267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.