ArticleAmerican journal of hypertension2018
Short-Term Blood Pressure Responses to Ambient Fine Particulate Matter Exposures at the Extremes of Global Air Pollution Concentrations.
Article in American journal of hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Acute Blood Pressure and Cardiovascular Effects of Near-Roadway Exposures With and Without N95 Respirators.American journal of hypertension · 2019Trial
- Effects of Short-Term Exposure to Air Pollutants on Real-Time Blood Pressure: A Wearable Device-Based Study in China.Journal of urban health : bulletin of the New York Academy of Medicine · 2025Article
- Air pollution and the number of daily visits of hypertension in northern china: a time-series analysis on generalized additive model.Scientific reports · 2025Article
- Integrating 4-D light-sheet fluorescence microscopy and genetic zebrafish system to investigate ambient pollutants-mediated toxicity.The Science of the total environment · 2023Review
- Environmental exposures and blood pressure in adolescents and adults in the T1D exchange clinic registry.Journal of diabetes and its complications · 2023Article
- Association between ambient particulate matter levels and hypertension: results from the Korean Genome and Epidemiology Study.Annals of occupational and environmental medicine · 2023Article
- Seasonal variation in blood pressure: what is still missing?Frontiers in cardiovascular medicine · 2023Review
- DNA methylation: a potential mediator between air pollution and metabolic syndrome.Clinical epigenetics · 2022Review
- Inhalation of particulate matter containing free radicals leads to decreased vascular responsiveness associated with an altered pulmonary function.American journal of physiology. Heart and circulatory physiology · 2021Article
- Advancing science and education through a novel collaboration platform between the University of Michigan and Peking University Health Science Center.FASEB bioAdvances · 2021Article
- Short-Term Effects of Particle Size and Constituents on Blood Pressure in Healthy Young Adults in Guangzhou, China.Journal of the American Heart Association · 2021Article
- Association of PMScientific reports · 2021Article
- Long-term effects of ambient PM2.5 on hypertension in multi-ethnic population from Sichuan province, China: a study based on 2013 and 2018 health service surveys.Environmental science and pollution research international · 2021Article
- Heterogeneous Urban Exposures and Prevalent Hypertension in the Helsinki Capital Region, Finland.International journal of environmental research and public health · 2021Article
- Association of short term exposure to Asian dust with increased blood pressure.Scientific reports · 2020Article
- The association between short-term exposure to extremely high level of ambient fine particulate matter and blood pressure: a panel study in Beijing, China.Environmental science and pollution research international · 2020Article
- Synergistic Effect of WTC-Particulate Matter and Lysophosphatidic Acid Exposure and the Role of RAGE: In-Vitro and Translational Assessment.International journal of environmental research and public health · 2020Article
- Organ-on-a-Chip: Opportunities for Assessing the Toxicity of Particulate Matter.Frontiers in bioengineering and biotechnology · 2020Review
- Association Between Metabolic and Hormonal Derangements and Professional Exposure to Urban Pollution in a High Intensity Traffic Area.Frontiers in endocrinology · 2020Article
- Short-term effects of ambient air pollution and outdoor temperature on biomarkers of myocardial damage, inflammation and oxidative stress in healthy adults.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
backgroundFine particulate matter (PM2.5) air pollution is a leading cause of global cardiovascular mortality. A key mechanism may be PM2.5-induced blood pressure (BP) elevations. Whether consistent prohypertensive responses persist across the breadth of worldwide pollution concentrations has never been investigated.
methodsWe evaluated the hemodynamic impact of short-term exposures to ambient PM2.5 in harmonized studies of healthy normotensive adults (4 BP measurements per participant) living in both a highly polluted (Beijing) and clean (Michigan) location.
resultsPrior 7-day outdoor-ambient and 24-hour personal-level PM2.5 concentration averages were much higher in Beijing (86.7 ± 52.1 and 52.4 ± 79.2 µg/m3) compared to Michigan (9.1 ± 1.8 and 12.2 ± 17.0 µg/m3). In Beijing (n = 73), increased outdoor-ambient exposures (per 10 µg/m3) during the prior 1-7 days were associated with significant elevations in diastolic BP (0.15-0.17 mm Hg). In overweight adults (body mass index ≥25 kg/m2), significant increases in both systolic (0.34-0.44 mm Hg) and diastolic (0.22-0.66 mm Hg) BP levels were observed. Prior 24-hour personal-level exposures also significantly increased BP (0.41/0.61 mm Hg) in overweight participants. Conversely, low PM2.5 concentrations in Michigan (n = 50), on average within Air Quality Guidelines, were not associated with BP elevations.
conclusionsOur findings demonstrate that short-term exposures to ambient PM2.5 in a highly polluted environment can promote elevations in BP even among healthy adults. The fact that no adverse hemodynamic responses were observed in a clean location supports the key public health importance of international efforts to improve air quality as part of the global battle against hypertension.
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