Evidence map›Paper›PMID 29409006›Full record

ArticleThe Journal of clinical endocrinology and metabolism2018

Vitamin D Status and Intakes and Their Association With Cognitive Trajectory in a Longitudinal Study of Urban Adults.

May A Beydoun, Sharmin Hossain, Marie T Fanelli-Kuczmarski, Hind A Beydoun, Jose-Atilio Canas, Michele K Evans, Alan B Zonderman

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Is There a Role of Vitamin D in Alzheimer's Disease?CNS & neurological disorders drug targets · 2024
    Review
  11. Review
  12. Vitamin DMetabolic brain disease · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Vitamin DFood science & nutrition · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

May A BeydounLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Intramural Research Program, Baltimore, Maryland.
Sharmin HossainLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Intramural Research Program, Baltimore, Maryland.
Marie T Fanelli-KuczmarskiDepartment of Behavioral Health and Nutrition, University of Delaware, Newark, Delaware.
Hind A BeydounDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Jose-Atilio CanasNemours Children's Clinic, Jacksonville, Florida.
Michele K EvansLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Intramural Research Program, Baltimore, Maryland.
Alan B ZondermanLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Intramural Research Program, Baltimore, Maryland.
National Institutes of Health · USJohns Hopkins University · USNational Institute on Aging · USNemours Children's Clinic · USUniversity of Delaware · US

Funding

Healthy Aging In Neighborhoods of Diversity Across the Life Span (HANDLS)ZIAAG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2009 to 2025
$70.9M
Age-associated cognitive changes in community dwelling adultsZIAAG000195 · NIA · NATIONAL INSTITUTE ON AGING · PI ZONDERMAN, ALAN B · 2009 to 2019
$9.3M
6 · The paper itself

Abstract

Context: Serum 25-hydroxyvitamin D [25(OH)D], and dietary and supplemental vitamin D may influence cognitive outcomes. Objectives: Sex-, age-, and race-specific associations of vitamin D status and intake with longitudinal change in various cognitive domains were examined in a large sample of ethnically and socioeconomically diverse US urban adults. Design: Two prospective waves of data from the Healthy Aging in Neighborhoods of Diversity across the Life Span study were used. Participants: Adults in Baltimore, Maryland, aged 30 to 64 years at baseline (n = 1231 to 1803), were followed for a mean (± standard deviation) of 4.64 ± 0.93 years. Visit 1 occurred between 2004 and 2009; visit 2, between 2009 and 2013; there were 1.5 to 2.0 visits per participant. Main outcome and exposure measures: Cognitive performance was assessed using 11 test scores covering domains of global cognition, attention, learning/memory, executive function, visuospatial/visuoconstruction ability, psychomotor speed, and language/verbal. Serum 25(OH)D, vitamin D intake, and use of supplements containing vitamin D were the key exposures. Results: A consistent relationship was found between vitamin D status (overall) and supplemental intake (older women and black adults), with a slower rate of decline in the domain of verbal fluency. Higher dietary intake of vitamin D was linked to slower rate of decline in verbal memory among younger women, and a slower rate of decline in visual memory/visuoconstructive abilities among white adults. All other associations were inconsistent. Conclusions: Vitamin D status and intakes were inversely related to domain-specific cognitive decline in US urban adults.

Indexed as

Dietary SupplementsAdultAgedAttentionCognitionCognitive DysfunctionExecutive FunctionFemaleHumansLearningLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsProspective StudiesReaction Time25-hydroxyvitamin DVitamin D

Identifiers

PMID29409006
PMCPMC6276714
OpenAlexW2791313798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.