Evidence map›Paper›PMID 29408538›Full record

ArticleArchives of physical medicine and rehabilitation2018

Lower Quadriceps Rate of Force Development Is Associated With Worsening Physical Function in Adults With or at Risk for Knee Osteoarthritis: 36-Month Follow-Up Data From the Osteoarthritis Initiative.

Bo Hu, Søren Thorgaard Skou, Barton L Wise, Glenn N Williams, Michael C Nevitt, Neil A Segal

2 registry-linked trialsOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04187092 nacompletednot on this mapstarted 2020, after this paper: background citation

Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy ("KneeBRIGHT") Phase II

TypeinterventionalSponsorUniversity of VirginiaRan2020 to 2021Enrolled38ConditionsOsteo Arthritis KneeArmsKneeBright Group, Standard Rehabilitation group
NCT04503304 nacompletednot on this mapstarted 2020, after this paper: background citation

Effect of Hip Abductors Versus Knee Extensor Strengthening on Pain,Function and Quadriceps Isometric Strength in Knee Osteoarthritis

TypeinterventionalSponsorCairo UniversityRan2020 to 2020Enrolled70ConditionsKnee OsteoarthritisArmsExercises
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

Bo HuDepartment of Rehabilitation Medicine, The University of Kansas, Kansas City, KS; School of Public Health and Hebei Province Key Laboratory of Occupational Health and Safety for Coal Industry, North China University of Science and Technology, Tangshan, Hebei Province, China.
Søren Thorgaard SkouResearch Unit for Musculoskeletal Function and Physiotherapy, Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark; Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospitals, Region Zealand, Slagelse, Denmark.
Barton L WiseUniversity of California, Davis School of Medicine, Sacramento, CA.
Glenn N WilliamsPhysical Therapy and Rehabilitation Sciences, Drexel University, Philadelphia, PA.
Michael C NevittDepartment of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, CA.
Neil A SegalDepartment of Rehabilitation Medicine, The University of Kansas, Kansas City, KS. Electronic address: segal-research@kumc.edu.
Drexel University · USNorth China University of Science and Technology · CNUniversity of California, Davis · USUniversity of California, San Francisco · USUniversity of Kansas · USUniversity of Southern Denmark · DK

Funding

DATA COORDINATING CENTER FOR THE OSTEOARTHRITIS INITIATIVE-264022258N01AR022258 · NIAMS · UNIVERSITY OF CALIFORNIA SYS OFFICE/PRES · 2003 to 2003
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CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-264022259-264022259N01AR022259 · NIAMS · UNIVERSITY OF MARYLAND AT BALT · PI HOCHBERG, MARC C. · 2002 to 2006
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CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-N01AR22260N01AR022260 · NIAMS · UNIVERSITY OF PITTSBURGH · PI KWOH, KENT · 2002 to 2006
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CLINICAL CENTERS FOR THE OSTEOARTHRITIS INITIATIVE-N01AR22261N01AR022261 · NIAMS · OHIO STATE UNIVERSITY RESEARCH · PI JACKSON, REBECCA · 2002 to 2006
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CLINICAL CENTER FOR THE OSTEOARTHRITIS-264022262-264022262N01AR022262 · NIAMS · THE MEMORIAL HOSPITAL · PI ASSAF, ANNLOUISE R. · 2002 to 2006
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NIAMS NIH HHS N01 AR022258NIAMS NIH HHS N01 AR022259NIAMS NIH HHS N01 AR022260NIAMS NIH HHS N01 AR022261NIAMS NIH HHS N01 AR022262
6 · The paper itself

Abstract

objectiveTo determine the association between quadriceps rate of force development (RFD) and decline in self-reported physical function and objective measures of physical performance.

designLongitudinal cohort study.

settingCommunity-based sample from 4 urban areas.

participantsOsteoarthritis Initiative participants with or at risk for knee osteoarthritis, who had no history of knee/hip replacement, knee injury, or rheumatoid arthritis (N=2630).

interventionsNot applicable.

main outcome measuresQuadriceps RFD (N/s) was measured during isometric strength testing. Worsening physical function was defined as the minimal clinically important difference for worsening self-reported Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) physical function subscale score, 20-m walk time, and repeated chair stand time over 36 months.

resultsCompared with the slowest tertile of RFD, the fastest tertile had a lower risk for worsening of WOMAC physical function subscale score at 36-month follow-up, with an odds ratio (OR) of .68 (95% confidence interval [CI], .51-.92) after adjustment for age, sex, body mass index, depression, history of chronic diseases, and knee pain. In women, in comparison with the slowest tertile of RFD, the fastest tertile had a lower risk for worsening of WOMAC physical function subscale score at 36-month follow-up, with an adjusted OR of .57 (95% CI, .38-.86). This decreased risk did not reach statistical significance in men (OR, 0.81; 95% CI, 0.52-1.27). No statistically significant associations were detected between baseline RFD and walk or chair stand times.

conclusionsOur results indicate that higher RFD is associated with decreased risk for worsening self-reported physical function but not with decreased risk for worsening of physical performance.

Indexed as

Knee JointPhysical Functional PerformanceAgedFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedOsteoarthritis, KneeQuadriceps MuscleRisk FactorsTime FactorsTorsion, MechanicalKneeMuscle StrengthOsteoarthritisQuadriceps muscleRehabilitationSports Medicine

Identifiers

PMID29408538
PMCPMC6019160
OpenAlexW2787617585

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.