Evidence map›Paper›PMID 29408202›Full record

ArticleFree radical biology & medicine2018

Resolvin D1 blocks H

Rima Chattopadhyay, Arul M Mani, Nikhlesh K Singh, Gadiparthi N Rao

Open access · greenAbstract read
In one paragraph

Article in Free radical biology & medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Roles of Resolvins in Chronic Inflammatory Response.International journal of molecular sciences · 2022
    Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Pro-resolving lipid mediators in vascular disease.The Journal of clinical investigation · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rima ChattopadhyayDepartment of Physiology, University of Tennessee Health Science Center, 71 S. Manassas Street, Memphis, TN 38163, USA.
Arul M ManiDepartment of Physiology, University of Tennessee Health Science Center, 71 S. Manassas Street, Memphis, TN 38163, USA.
Nikhlesh K SinghDepartment of Physiology, University of Tennessee Health Science Center, 71 S. Manassas Street, Memphis, TN 38163, USA.
Gadiparthi N RaoDepartment of Physiology, University of Tennessee Health Science Center, 71 S. Manassas Street, Memphis, TN 38163, USA. Electronic address: rgadipar@uthsc.edu.
University of Tennessee Health Science Center · US

Funding

Non-COX Arachidonic Acid Metabolites and AngiogenesisR01HL074860 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI RAO, GADIPARTHI N · 2004 to 2020
$5.9M
NHLBI NIH HHS R01 HL074860
6 · The paper itself

Abstract

In recent years, various studies have demonstrated a role for endogenously derived specialized proresolving mediators such as resolvins in the resolution of inflammation. In exploring the signaling mechanisms, in the present study we show that Resolvin D1 (RvD1) reduces LPS-induced endothelial cell (EC)-monocyte interactions via blocking H

Indexed as

Docosahexaenoic AcidsHumansHuman Umbilical Vein Endothelial CellsHydrogen PeroxideInflammationInflammation MediatorsMonocytesOxidantsProtein Phosphatase 2Protein Tyrosine Phosphatase, Non-Receptor Type 11Receptor Cross-TalkReceptors, G-Protein-CoupledSignal TransductionDocosahexaenoic AcidsGPR32 protein, humanHydrogen PeroxideInflammation MediatorsOxidantsProtein Phosphatase 2Protein Tyrosine Phosphatase, Non-Receptor Type 11Receptors, G-Protein-Coupledresolvin D1Endothelial cellsICAM1NFkappaBPP2AResolvin D1VCAM1

Identifiers

PMID29408202
PMCPMC5845835
OpenAlexW2791107553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.