Evidence map›Paper›PMID 29407163›Full record

ArticleToxicon : official journal of the International Society on Toxinology2018

Intraspecies geographical variability in the South American tigra mariposa (Bothrops venezuelensis Sandner 1952) snake venom activities.

María E Girón, Vanessa Padrón, María I Ramos, Elda E Sánchez, Belsy Guerrero, Alberto García, Néstor L Uzcátegui, Luis F Navarrete, Alexis Rodríguez-Acosta

Abstract read
In one paragraph

Article in Toxicon : official journal of the International Society on Toxinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Venom composition ofThe journal of venomous animals and toxins including tropical diseases · 2022
    Article
  3. Bleeding and Thrombosis: Insights into Pathophysiology ofInternational journal of molecular sciences · 2021
    Review
  4. The neutralization efficacy of expired polyvalent antivenoms: An alternative option.Toxicon : official journal of the International Society on Toxinology · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

María E GirónLaboratorio de Inmunoquimica y Ultraestructura, Instituto Anatómico, Universidad Central de Venezuela, Caracas, Venezuela.
Vanessa PadrónLaboratorio de Inmunoquimica y Ultraestructura, Instituto Anatómico, Universidad Central de Venezuela, Caracas, Venezuela.
María I RamosLaboratorio de Inmunoquimica y Ultraestructura, Instituto Anatómico, Universidad Central de Venezuela, Caracas, Venezuela.
Elda E SánchezNational Natural Toxins Research Center (NTRC), Texas A&M University-Kingsville, MSC 158, Kingsville, TX 78363, USA.
Belsy GuerreroLaboratorio de Fisiopatología, Centro de Medicina Experimental, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Venezuela.
Alberto GarcíaCátedra de Fisiología, Instituto de Medicina Experimental de la Universidad Central de Venezuela, Caracas, Venezuela.
Néstor L UzcáteguiLaboratorio de Inmunoquimica y Ultraestructura, Instituto Anatómico, Universidad Central de Venezuela, Caracas, Venezuela.
Luis F NavarreteLaboratorio de Inmunoquimica y Ultraestructura, Instituto Anatómico, Universidad Central de Venezuela, Caracas, Venezuela.
Alexis Rodríguez-AcostaLaboratorio de Inmunoquimica y Ultraestructura, Instituto Anatómico, Universidad Central de Venezuela, Caracas, Venezuela. Electronic address: rodriguezacosta1946@yahoo.es.

Funding

Viper Resource Grant at Texas A&M University-KingsvilleP40OD010960 · OD · TEXAS A&M UNIVERSITY-KINGSVILLE · PI Elda E. Sanchez · 2012 to 2026
$9.2M
NIH HHS P40 OD010960
6 · The paper itself

Abstract

Bothrops venezuelensis snake venoms, from five localities in the North-Central Venezuelan regions, showed biochemical and haemostatic differences. In this study, bioactivities of B. venezuelensis venoms from different regions (Aragua state; Waraira Repano (Capital District); Baruta, La Boyera and Lagunetica (Miranda state)) were compared using both natural and synthetic substrates. The protein contents of these venoms were Lagunetica 89%, La Boyera 79%, Baruta 71%, Waraira Repano 68% and Aragua 64%. Toxic activities effects were: Intraperitoneal LD

Indexed as

BothropsAnimalsBlood CoagulationCaseinsCrotalid VenomsFibrinogenFibrinolysisGeographyHemorrhageLethal Dose 50MiceProteolysisVenezuelaCaseinsCrotalid VenomsFibrinogenBothrops venezuelensisFibrino(geno)lyticFibrinolyticIntraspecies variabilityProteolytic

Identifiers

PMID29407163
PMCPMC6380184

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.