Evidence map›Paper›PMID 29406961›Full record

ArticleJournal of the neurological sciences2018

Feasibility study of a targeted self-management intervention for reducing stroke risk factors in a high-risk population in Uganda.

Mark Kaddumukasa, Jane Nakibuuka, Levicatus Mugenyi, Olivia Namusoke, Doreen Birungi, Bryan Kabaala, Carol Blixen, Elly Katabira, Anthony Furlan, Martha Sajatovic

Open access · greenAbstract read
In one paragraph

Article in Journal of the neurological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Mark KaddumukasaDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda. Electronic address: mkaddumukasa@chs.mak.ac.ug.
Jane NakibuukaDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Levicatus MugenyiDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Olivia NamusokeDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Doreen BirungiDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Bryan KabaalaDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Carol BlixenDepartment of Neurology, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address: cxb28@case.edu.
Elly KatabiraDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda. Electronic address: katabira@imul.com.
Anthony FurlanDepartment of Neurology, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address: Anthony.furlan@uhhospitals.org.
Martha SajatovicDepartment of Neurology, Department of Psychiatry, Case Western Reserve University School of Medicine, Neurological and Behavioral Outcomes Center, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address: Martha.Sajatovic@UHhospitals.org.
Makerere University · UGUniversity Hospitals of Cleveland · US

Funding

Reducing stroke burden in UgandaR21NS094022 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI KATABIRA, ELLY T, SAJATOVIC, MARTHA X · 2015 to 2016
$323k
NINDS NIH HHS R21 NS094022
6 · The paper itself

Abstract

introductionStroke remains a global concern due to increasing lifespan, patterns of industrialization, adoption of harmful western diets, and an increasing prevalence of risk factors such as hypertension, obesity, and diabetes. We investigated an adopted novel self-management intervention, TargetEd mAnageMent Intervention (TEAM) to reduce modifiable stroke risk factors in Uganda.

methodsA six-month, uncontrolled, prospective pilot study to establish feasibility, acceptability and preliminary efficacy of TEAM in Ugandans at high risk for stroke was conducted. The primary outcome was change in systolic BP from baseline to 24-week follow-up. Secondary outcomes included change in diastolic BP, serum cholesterol, high and low density lipoprotein (HDL, LDL) and triglycerides.

resultsMean (SD) baseline systolic BP was 162.9 (±25.6) mmHg while mean (SD) baseline diastolic BP was 99.1 (±13.8) mmHg. There was a significant reduction in mean baseline blood pressure of 163/98.8mmHg to blood pressure of 147.8/88.0mmHg at 24weeks, P=0.023. There were also significant reductions in the serum total cholesterol levels at 24weeks with P=0.001.

conclusionTargeted training in self-management (TEAM) adapted to the Ugandan setting is feasible, highly acceptable to participants and appears to be associated with reduced blood pressure, improved lipid profiles and improved glucose control in diabetics.

Indexed as

AdultAge FactorsBlood PressureCholesterol, LDLFeasibility StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedOutcome Assessment, Health CarePilot ProjectsRisk FactorsSelf-ManagementStrokeTime FactorsCholesterol, LDLBlood pressurePreventionRisk factorsStroke

Identifiers

PMID29406961
PMCPMC5804990
OpenAlexW2781992654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.