Evidence map›Paper›PMID 29406789›Full record

ArticleDiabetes technology & therapeutics2018

Automatic Detection and Estimation of Unannounced Meals for Multivariable Artificial Pancreas System.

Sediqeh Samadi, Mudassir Rashid, Kamuran Turksoy, Jianyuan Feng, Iman Hajizadeh, Nicole Hobbs, Caterina Lazaro, Mert Sevil, Elizabeth Littlejohn, Ali Cinar

Open access · greenAbstract read
In one paragraph

Article in Diabetes technology & therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 89 citations in OpenAlex.

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  5. Metabolic Models, in Silico Trials, and Algorithms.Diabetes technology & therapeutics · 2025
    Review
  6. Metabolic Models, in Silico Trials, and Algorithms.Journal of diabetes science and technology · 2025
    Review
  7. Dosing Algorithms for Insulin Pumps.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
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  12. Diabetes management in the era of artificial intelligence.Archives of medical sciences. Atherosclerotic diseases · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. A New Meal Absorption Model for Artificial Pancreas Systems.Journal of diabetes science and technology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sediqeh Samadi1 Department of Chemical and Biological Engineering, Illinois Institute of Technology , Chicago, Illinois.
Mudassir Rashid1 Department of Chemical and Biological Engineering, Illinois Institute of Technology , Chicago, Illinois.
Kamuran Turksoy2 Department of Biomedical Engineering, Illinois Institute of Technology , Chicago, Illinois.
Jianyuan Feng1 Department of Chemical and Biological Engineering, Illinois Institute of Technology , Chicago, Illinois.
Iman Hajizadeh1 Department of Chemical and Biological Engineering, Illinois Institute of Technology , Chicago, Illinois.
Nicole Hobbs2 Department of Biomedical Engineering, Illinois Institute of Technology , Chicago, Illinois.
Caterina Lazaro3 Department of Electrical and Computer Engineering, Illinois Institute of Technology , Chicago, Illinois.
Mert Sevil2 Department of Biomedical Engineering, Illinois Institute of Technology , Chicago, Illinois.
Elizabeth Littlejohn4 Department of Pediatrics and Medicine, Kovler Diabetes Center, University of Chicago , Chicago, Illinois.
Ali Cinar1 Department of Chemical and Biological Engineering, Illinois Institute of Technology , Chicago, Illinois.
Illinois Institute of Technology · US

Funding

Control Systems for Artificial Pancreas Use During and After ExerciseDP3DK101075 · NIDDK · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CINAR, ALI · 2013 to 2013
$2.5M
Fault-tolerant Control Systems for Artificial PancreasDP3DK101077 · NIDDK · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CINAR, ALI · 2013 to 2013
$2.0M
NIDDK NIH HHS DP3 DK101075NIDDK NIH HHS DP3 DK101077
6 · The paper itself

Abstract

backgroundAutomatically attenuating the postprandial rise in the blood glucose concentration without manual meal announcement is a significant challenge for artificial pancreas (AP) systems. In this study, a meal module is proposed to detect the consumption of a meal and to estimate the amount of carbohydrate (CHO) intake.

methodsThe meals are detected based on qualitative variables describing variation of continuous glucose monitoring (CGM) readings. The CHO content of the meals/snacks is estimated by a fuzzy system using CGM and subcutaneous insulin delivery data. The meal bolus amount is computed according to the patient's insulin to CHO ratio. Integration of the meal module into a multivariable AP system allows revision of estimated CHO based on knowledge about physical activity, sleep, and the risk of hypoglycemia before the final decision for a meal bolus is made.

resultsThe algorithm is evaluated by using 117 meals/snacks in retrospective data from 11 subjects with type 1 diabetes. Sensitivity, defined as the percentage of correctly detected meals and snacks, is 93.5% for meals and 68.0% for snacks. The percentage of false positives, defined as the proportion of false detections relative to the total number of detected meals and snacks, is 20.8%.

conclusionsIntegration of a meal detection module in an AP system is a further step toward an automated AP without manual entries. Detection of a consumed meal/snack and infusion of insulin boluses using an estimate of CHO enables the AP system to automatically prevent postprandial hyperglycemia.

Indexed as

MealsPancreas, ArtificialAdolescentAdultBlood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1FemaleHumansHypoglycemiaHypoglycemic AgentsInsulinMalePostprandial PeriodRetrospective StudiesTreatment OutcomeBlood GlucoseHypoglycemic AgentsInsulinArtificial pancreasFuzzy estimation.Meal detectionMeal size estimationQualitative representation

Identifiers

PMID29406789
PMCPMC5867514
OpenAlexW2787649434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.