Evidence map›Paper›PMID 29406722›Full record

ArticleThe Journal of organic chemistry2018

Access to Bicyclo[4.2.0]octene Monomers To Explore the Scope of Alternating Ring-Opening Metathesis Polymerization.

Lei Chen, Liqiang Li, Nicole S Sampson

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lei ChenDepartment of Chemistry, Stony Brook University , Stony Brook, New York 11794-3400, United States.ORCID 0000-0003-3361-0705
Liqiang LiDepartment of Chemistry, Stony Brook University , Stony Brook, New York 11794-3400, United States.
Nicole S SampsonDepartment of Chemistry, Stony Brook University , Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-2835-7760

Funding

Polymer Probes of Cell-Cell InteractionsR01GM097971 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI SAMPSON, NICOLE S · 2011 to 2020
$2.3M
NIGMS NIH HHS R01 GM097971
6 · The paper itself

Abstract

Bicyclo[4.2.0]oct-1(8)-ene-8-carboxamides undergo alternating ring-opening metathesis polymerization (AROMP) with cyclohexene. Herein, a general method for the preparation of bicyclo[4.2.0]oct-(8)-ene-8-carboxy derivatives is described. The central 8-cyano intermediate provides entry to five different functional group substituents on the alkene. These monomers were tested as potential substrates for AROMP with cyclohexene. In addition to the carboxamide, the carboxynitrile and carboxaldehyde are also substrates for AROMP. In the case of the carboxaldehyde, the polymer is regioregular. However, the addition of carboxynitrile is stereoirregular and slow.

Indexed as

PolymerizationAldehydesAlkenesBridged Bicyclo Compounds, HeterocyclicEstersNitrilesAldehydesAlkenesBridged Bicyclo Compounds, HeterocyclicEstersNitriles

Identifiers

PMID29406722
PMCPMC5838619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.