Evidence map›Paper›PMID 29406721›Full record

ArticleNano letters2018

Gold Nanorod-Based Engineered Cardiac Patch for Suture-Free Engraftment by Near IR.

Maayan Malki, Sharon Fleischer, Assaf Shapira, Tal Dvir

Abstract read
In one paragraph

Article in Nano letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

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  13. Nanomedicines for cardiovascular disease.Nature cardiovascular research · 2023
    Review
  14. Construction of a Band-Aid Like Cardiac Patch for Myocardial Infarction with Controllable HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maayan MalkiThe Department of Materials Science and Engineering, Faculty of Engineering , Tel Aviv University , Tel Aviv 6997801 , Israel.
Sharon FleischerThe Center for Nanoscience and Nanotechnology , Tel Aviv University , Tel Aviv 6997801 , Israel.
Assaf ShapiraThe Center for Nanoscience and Nanotechnology , Tel Aviv University , Tel Aviv 6997801 , Israel.
Tal DvirThe Department of Materials Science and Engineering, Faculty of Engineering , Tel Aviv University , Tel Aviv 6997801 , Israel.ORCID 0000-0002-3153-9928

Funding

European Research Council 637943
6 · The paper itself

Abstract

Although cardiac patches hold a promise for repairing the infarcted heart, their integration with the myocardium by sutures may cause further damage to the diseased organ. To address this issue, we developed facile and safe, suture-free technology for the attachment of engineered tissues to organs. Here, nanocomposite scaffolds comprised of albumin electrospun fibers and gold nanorods (AuNRs) were developed. Cardiac cells were seeded within the scaffolds and assembled into a functioning patch. The engineered tissue was then positioned on the myocardium and irradiated with a near IR laser (808 nm). The AuNRs were able to absorb the light and convert it to thermal energy, which locally changed the molecular structure of the fibrous scaffold, and strongly, but safely, attached it to the wall of the heart. Such hybrid biomaterials can be used in the future to integrate any engineered tissue with any defected organs, while minimizing the risk of additional injury for the patient, caused by the conventional stitching methods.

Indexed as

AlbuminsAnimalsBiocompatible MaterialsCardiac Surgical ProceduresDisease Models, AnimalGoldHeartHumansMyocardial InfarctionNanocompositesNanotubesRatsSuturesTissue EngineeringTissue ScaffoldsAlbuminsBiocompatible MaterialsGoldCardiac tissue engineeringengraftmentgold nanorodsnear IRtissue integration

Identifiers

PMID29406721
PMCPMC6047511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.