Evidence map›Paper›PMID 29406438›Full record

ReviewCurrent opinion in pediatrics2018

The child health exposure analysis resource as a vehicle to measure environment in the environmental influences on child health outcomes program.

Robert O Wright, Susan Teitelbaum, Claudia Thompson, David Balshaw, CHEAR Network

Registry-linked trialAbstract readReview
In one paragraph

Review in Current opinion in pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03061890 (Developmental Impact of Neonatal Intensive Care Unit), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03061890 completednot on this map

Developmental Impact of Neonatal Intensive Care Unit (NICU) Exposures: Environmental Influences on Child Health Outcomes (ECHO)

Typeobservational_patient_registrySponsorAlbert Einstein College of MedicineRan2017 to 2023Enrolled600ConditionsPrematurity
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  8. Advancing Exposomic Research in Prenatal Respiratory Disease Programming.Immunology and allergy clinics of North America · 2023
    Review
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  11. Review
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Robert O WrightIcahn School of Medicine at Mount Sinai, New York City, New York.
Susan TeitelbaumIcahn School of Medicine at Mount Sinai, New York City, New York.
Claudia ThompsonNational Institute of Environmental Health Science, Research Triangle Park, North Carolina, USA.
David BalshawNational Institute of Environmental Health Science, Research Triangle Park, North Carolina, USA.
CHEAR Network
Icahn School of Medicine at Mount Sinai · USNational Institute of Environmental Health Sciences · USTriangle · US

Funding

Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
Statistical Services and Methods Development ResourceU2CES026555 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GENNINGS, CHRIS · 2015 to 2025
$26.4M
Untargeted Analysis ResourceU2CES026561 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROBERT O · 2015 to 2025
$24.5M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUG3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CARROLL, KECIA NICOLE, WRIGHT, ROBERT O · 2016 to 2024
$20.6M
Developmental Impact of NICU Exposures (DINE)UH3OD023320 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ASCHNER, JUDY LYNN, STROUSTRUP, ANNEMARIE · 2018 to 2022
$14.5M
Human Health Exposure Analysis Resource (HHEAR): Coordinating CenterU24ES026539 · NIEHS · WESTAT, INC. · PI MERRILL, LORI · 2015 to 2025
$10.8M
Developmental Impact of NICU Exposures (DINE)UG3OD023320 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ASCHNER, JUDY LYNN, TEITELBAUM, SUSAN L · 2016 to 2017
$6.1M
NIEHS NIH HHS U24 ES026539NIEHS NIH HHS U2C ES026555NIEHS NIH HHS U2C ES026561NIH HHS UG3 OD023320NIH HHS UG3 OD023337NIH HHS UH3 OD023320NIH HHS UH3 OD023337
6 · The paper itself

Abstract

purpose of reviewDemonstrate the role of environment as a predictor of child health. RECENT

findingsThe children's health exposure analysis resource (CHEAR) assists the Environmental influences on child health outcomes (ECHO) program in understanding the time sensitive and dynamic nature of perinatal and childhood environment on developmental trajectories by providing a central infrastructure for the analysis of biological samples from the ECHO cohort awards. CHEAR will assist ECHO cohorts in defining the critical or sensitive period for effects associated with environmental exposures. Effective incorporation of these principles into multiple existing cohorts requires extensive multidisciplinary expertise, creativity, and flexibility. The pursuit of life course - informed research within the CHEAR/ECHO structure represents a shift in focus from single exposure inquiries to one that addresses multiple environmental risk factors linked through shared vulnerabilities. CHEAR provides ECHO both targeted analyses of inorganic and organic toxicants, nutrients, and social-stress markers and untargeted analyses to assess the exposome and discovery of exposure-outcome relationships. SUMMARY: Utilization of CHEAR as a single site for characterization of environmental exposures within the ECHO cohorts will not only support the investigation of the influence of environment on children's health but also support the harmonization of data across the disparate cohorts that comprise ECHO.

Indexed as

Child HealthEnvironmental HealthNational Institutes of Health (U.S.)Research DesignBiomedical ResearchChildEnvironmental ExposureEnvironmental MonitoringHumansUnited States

Identifiers

PMID29406438
PMCPMC5947863
OpenAlexW2792214081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.