ArticlePhysiological measurement2018
A microbeam grazing-incidence approach to L-shell x-ray fluorescence measurements of lead concentration in bone and soft tissue phantoms.
Article in Physiological measurement, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Portable x-ray fluorescence for bone lead measurement: Current approaches and future directions.Current environmental health reports · 2024Review
- A novel calibration for L-shell x-ray fluorescence measurements of bone lead concentration using the strontium KPhysiological measurement · 2021Article
- Improvements and reproducibility of an optimal grazing-incidence position method to L-shell x-ray fluorescence measurements of lead in bone and soft tissue phantoms.Biomedical physics & engineering express · 2018Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
objectiveL-shell x-ray fluorescence (LXRF) is a non-invasive approach to lead (Pb) concentration measurements in the human bone. The first studies were published in the early 1980s. In the same period the K-shell x-ray fluorescence (KXRF) method using a Cd-109 radionuclide source was developed and later improved and refined. Lower sensitivity and calibration difficulties associated with the LXRF method led the KXRF to be the most adopted method for in vivo human bone Pb studies. In the present study a microbeam-based grazing-incidence approach to Pb LXRF measurements was investigated. APPROACH: The microbeam produced by an integrated x-ray tube and polycapillary x-ray lens (PXL) unit was used to excite cylindrical plaster-of-Paris (poP) bone phantoms doped with Pb in seven concentrations: 0, 8, 16, 29, 44, 59, and 74 µg g MAIN
resultsThe lowest detection limit (DL) values were (2.9 ± 0.2), (4.9 ± 0.3), and (23 ± 3) µg g SIGNIFICANCE: The results are superior to a relatively recently published LXRF phantom study and show promise for future designs of in vivo LXRF measurements.
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