Evidence map›Paper›PMID 29406006›Full record

ReviewClinics in perinatology2018

Neonatal Diabetes Mellitus: An Update on Diagnosis and Management.

Michelle Blanco Lemelman, Lisa Letourneau, Siri Atma W Greeley

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it, 192 citations in OpenAlex.

  1. Clinical and Genetic Characteristics ofJournal of diabetes research · 2021
    Pooled it
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  6. Permanent Neonatal Diabetes with High Insulin Requirements due to a New Variant in theJournal of clinical research in pediatric endocrinology · 2026
    Article
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michelle Blanco LemelmanSection of Adult and Pediatric Endocrinology, Diabetes, and Metabolism, MC 5053, 5841 South Maryland Avenue, Chicago, IL 60637, USA.
Lisa LetourneauMonogenic Diabetes Registry, University of Chicago Medicine, Kovler Diabetes Center, 900 East 57th Street, Chicago, IL 60637, USA.
Siri Atma W GreeleySection of Adult and Pediatric Endocrinology, Diabetes, and Metabolism, Kovler Diabetes Center, The University of Chicago, 900 East 57th Street, Chicago, IL 60637, USA. Electronic address: sgreeley@peds.bsd.uchicago.edu.
University of Chicago · US

Funding

Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI RONALD N COHEN · 2013 to 2026
$20.9M
Monogenic Diabetes: Next Generation Diagnosis, Treatment and ComplicationsR01DK104942 · NIDDK · UNIVERSITY OF CHICAGO · PI GREELEY, SIRI ATMA W., PHILIPSON, LOUIS H. · 2016 to 2024
$4.7M
Pediatric Endocrinology Research Training GrantT32DK064582 · NIDDK · UNIVERSITY OF CHICAGO · PI PHILIPSON, LOUIS H. · 2004 to 2018
$1.9M
Incretin Regulation of Insulin Secretion in Human Neonatal DiabetesK23DK094866 · NIDDK · UNIVERSITY OF CHICAGO · PI GREELEY, SIRI ATMA W. · 2012 to 2014
$515k
NIDDK NIH HHS K23 DK094866NIDDK NIH HHS P30 DK020595NIDDK NIH HHS R01 DK104942NIDDK NIH HHS T32 DK064582
6 · The paper itself

Abstract

Neonatal diabetes mellitus is likely to be due to an underlying monogenic defect when it occurs at less than 6 months of age. Early recognition and urgent genetic testing are important for predicting the clinical course and raising awareness of possible additional features. Early treatment of sulfonylurea-responsive types of neonatal diabetes may improve neurologic outcomes. It is important to distinguish neonatal diabetes mellitus from other causes of hyperglycemia in newborns. Other causes include infection, stress, inadequate pancreatic insulin production in preterm infants, among others. This review explores the diagnostic approach, mutation types, management, and clinical course of neonatal diabetes.

Indexed as

Diabetes MellitusHumansHyperglycemiaHypoglycemic AgentsInfant, Extremely PrematureInfant, NewbornInfant, PrematureInsulinMutationSulfonylurea CompoundsHypoglycemic AgentsInsulinSulfonylurea CompoundsGeneticGlyburideInsulinMonogenic diabetesNeonatal diabetes

Identifiers

PMID29406006
PMCPMC5928785
OpenAlexW2772619423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.