Evidence map›Paper›PMID 29405921›Full record

ArticleBehavior therapy2018

Benchmarking Treatment Response in Tourette's Disorder: A Psychometric Evaluation and Signal Detection Analysis of the Parent Tic Questionnaire.

Emily J Ricketts, Joseph F McGuire, Susanna Chang, Deepika Bose, Madeline M Rasch, Douglas W Woods, Matthew W Specht, John T Walkup, Lawrence Scahill, Sabine Wilhelm and 2 more

Abstract read
In one paragraph

Article in Behavior therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Childhood cognitive control as a predictor of long-term clinical and functional outcomes in Tourette syndrome.Journal of child psychology and psychiatry, and allied disciplines · 2026
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  11. Automated Quantification of Eye Tics Using Computer Vision and Deep Learning Techniques.Movement disorders : official journal of the Movement Disorder Society · 2024
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Emily J RickettsUniversity of California, Los Angeles. Electronic address: ericketts@mednet.ucla.edu.
Joseph F McGuireUniversity of California, Los Angeles.
Susanna ChangUniversity of California, Los Angeles.
Deepika BoseUniversity of California, Los Angeles.
Madeline M RaschUniversity of California, Los Angeles.
Douglas W WoodsMarquette University.
Matthew W SpechtJohns Hopkins University.
John T WalkupWeill Cornell Medical College.
Lawrence ScahillEmory University School of Medicine.
Sabine WilhelmMassachusetts General Hospital/Harvard Medical School.
Alan L PetersonUniversity of Texas Health Science Center at San Antonio.
John PiacentiniUniversity of California, Los Angeles.

Funding

TRAINING THE SCIENCE OF CHILD MENTAL HEALTH TREATMENTT32MH073517 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUMA JACOB, John C. Piacentini · 2006 to 2026
$5.2M
Behavior Therapy for Children with Chronic Tic DisordersR01MH070802 · NIMH · TOURETTE SYNDROME ASSOCIATION, INC · PI PIACENTINI, JOHN C. · 2004 to 2007
$2.9M
NIMH NIH HHS R01 MH070802NIMH NIH HHS T32 MH073517
6 · The paper itself

Abstract

This study assessed the psychometric properties of a parent-reported tic severity measure, the Parent Tic Questionnaire (PTQ), and used the scale to establish guidelines for delineating clinically significant tic treatment response. Participants were 126 children ages 9 to 17 who participated in a randomized controlled trial of Comprehensive Behavioral Intervention for Tics (CBIT). Tic severity was assessed using the Yale Global Tic Severity Scale (YGTSS), Hopkins Motor/Vocal Tic Scale (HMVTS) and PTQ; positive treatment response was defined by a score of 1 (very much improved) or 2 (much improved) on the Clinical Global Impressions - Improvement (CGI-I) scale. Cronbach's alpha and intraclass correlations (ICC) assessed internal consistency and test-retest reliability, with correlations evaluating validity. Receiver- and Quality-Receiver Operating Characteristic analyses assessed the efficiency of percent and raw-reduction cutoffs associated with positive treatment response. The PTQ demonstrated good internal consistency (α = 0.80 to 0.86), excellent test-retest reliability (ICC = .84 to .89), good convergent validity with the YGTSS and HM/VTS, and good discriminant validity from hyperactive, obsessive-compulsive, and externalizing (i.e., aggression and rule-breaking) symptoms. A 55% reduction and 10-point decrease in PTQ Total score were optimal for defining positive treatment response. Findings help standardize tic assessment and provide clinicians with greater clarity in determining clinically meaningful tic symptom change during treatment.

Indexed as

BenchmarkingParentsSeverity of Illness IndexSignal Detection, PsychologicalAdolescentChildFemaleHumansMalePsychometricsReproducibility of ResultsSurveys and QuestionnairesTourette Syndromepsychometricsreceiver operating characteristicTourette’s disorder

Identifiers

PMID29405921
PMCPMC5988429

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.