Evidence map›Paper›PMID 29405914›Full record

ArticleeLife2018

Juan Carlos Lopez-Baez, Daniel J Simpson, Laura LLeras Forero, Zhiqiang Zeng, Hannah Brunsdon, Angela Salzano, Alessandro Brombin, Cameron Wyatt, Witold Rybski, Leonie F A Huitema and 7 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Regeneration in fish, with special focus on killifishes.Fish physiology and biochemistry · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Development of a straight vertebrate body axis.Development (Cambridge, England) · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. TheBiology open · 2019
    Article
  11. Article
  12. Article
  13. Tissue self-organization underlies morphogenesis of the notochord.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 5 countries.

Juan Carlos Lopez-BaezMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Daniel J Simpson *MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Laura LLeras Forero *Hubrecht Institute - KNAW & UMC Utrecht, Utrecht, Netherlands.
Zhiqiang ZengMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Hannah BrunsdonMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Angela SalzanoMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Alessandro BrombinMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0001-8262-9248
Cameron WyattMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Witold RybskiMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0002-6025-2918
Leonie F A HuitemaHubrecht Institute - KNAW & UMC Utrecht, Utrecht, Netherlands.
Rodney M DaleDepartment of Biology, Loyola University Chicago, Chicago, United States.ORCID https://orcid.org/0000-0003-4255-4741
Koichi KawakamiDivision of Molecular and Developmental Biology, National Institute of Genetics, Mishima, Japan.ORCID http://orcid.org/0000-0001-9993-1435
Christoph EnglertDepartment of Molecular Genetics, Leibniz Institute for Age Research-Fritz Lipmann Institute, Jena, Germany.ORCID http://orcid.org/0000-0002-5931-3189
Tamir ChandraMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Stefan Schulte-MerkerHubrecht Institute - KNAW & UMC Utrecht, Utrecht, Netherlands.ORCID http://orcid.org/0000-0003-3617-8807
Nicholas D HastieMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
E Elizabeth PattonMRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0002-2570-0834
Institute of Genetics and Cancer · GBUniversity Medical Center Utrecht · NLLeibniz Institute on Aging - Fritz Lipmann Institute (FLI) · DELoyola University Chicago · USNational Institute of Genetics · JP

Funding

European Research Council ZF-MEL-CHEMBIO - 648489Medical Research Council Discovery Award MC_PC_15075Medical Research Council Doctoral Training Programme in Percision MedicineMedical Research Council MC_PC_15075Medical Research Council MC_PC_U127527180Medical Research Council MC_PC_U127585840Medical Research Council MC_UU_00007/9Medical Research Council U127527202
6 · The paper itself

Abstract

Regenerative therapy for degenerative spine disorders requires the identification of cells that can slow down and possibly reverse degenerative processes. Here, we identify an unanticipated wound-specific notochord sheath cell subpopulation that expresses Wilms Tumor (WT) 1b following injury in zebrafish. We show that localized damage leads to Wt1b expression in sheath cells, and that

Indexed as

Nerve RegenerationWound HealingAnimalsCell MovementNeurogliaNotochordWT1 ProteinsZebrafishWT1 Proteinsdevelopmental biologyheterogeneitynotochordsheath cellsstem cellsvertebraeWilms Tumor 1wound healingzebrafish

Identifiers

PMID29405914
PMCPMC5811212
OpenAlexW2745307125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.