Evidence map›Paper›PMID 29405040›Full record

ArticleJournal of Zhejiang University. Science. B

Phytochemical composition, biological potential and enzyme inhibition activity of Scandix pecten-veneris L.

Abdul Wahab, Syed Aleem Jan, Abdur Rauf, Zia Ur Rehman, Zahid Khan, Aftab Ahmed, Fatima Syed, Sher Zaman Safi, Hamayun Khan, Muhammad Imran

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In one paragraph

Article in Journal of Zhejiang University. Science. B. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abdul WahabDepartment of Chemistry, Islamia College University, Peshawar-25120 KP, Pakistan.
Syed Aleem JanBiochemistry Section Institute of Chemical Sciences, University of Peshawar, Peshawar-25120 KP, Pakistan.
Abdur RaufDepartment of Chemistry, University of Swabi, Anbar-23561 KP, Pakistan.
Zia Ur RehmanDepartment of Botany, Islamia College University, Peshawar-25120 KP, Pakistan.
Zahid KhanBiochemistry Section Institute of Chemical Sciences, University of Peshawar, Peshawar-25120 KP, Pakistan.
Aftab AhmedState Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
Fatima SyedBiochemistry Section Institute of Chemical Sciences, University of Peshawar, Peshawar-25120 KP, Pakistan.
Sher Zaman SafiInterdisciplinary Research Center in Biomedical Materials, COMSATS Institute of Information Technology, Lahore-54000, Pakistan.
Hamayun KhanDepartment of Chemistry, Islamia College University, Peshawar-25120 KP, Pakistan.
Muhammad ImranBiochemistry Section Institute of Chemical Sciences, University of Peshawar, Peshawar-25120 KP, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveScandix pecten-veneris L. is a less studied wild edible herb and is considered an extinct plant species in many parts of the world. This study was designed to evaluate its phytochemical composition and biological potential of S. pecten-veneris L.

methodsPhytochemicals including alkaloids, flavonoids, polyphenols, and tannins were determined in extracts of S. pecten-veneris. Antioxidant activity was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), while reducing power was tested by ferric reducing/antioxidant power (FRAP) assay. Antimicrobial activity against seven bacterial and four fungal strains was evaluated using agar well diffusion assay. Enzymes inhibition study was performed for urease, phosphodiesterase-I, and catalase-II.

resultsS. pecten-veneris showed moderate antiradical activity and reducing potential of hydroxyl radicals to about 20% of the initial value. The antioxidant activity of various extracts of S. pecten-veneris showed a linear correlation with total phenolic contents in the order of water>n-butanol>chloroform>ethyl acetate>methanol extracts. S. pecten-veneris leaves showed the highest inhibitory activity against Staphylococcus aureus while the highest antifungal activity was observed against Candida albicans. The plant extract was most potent against urease enzymes but showed moderate activity against phosphodiestrase-I and carbonic anhydrase-II.

conclusionsOur data demonstrate that in addition to its culinary uses, S. pecten-veneris has good medicinal potential and hence could be used for treating some specific health ailments.

Indexed as

AnimalsAnti-Infective AgentsAntioxidantsApiaceaeEnzyme InhibitorsPhosphodiesterase InhibitorsPhytochemicalsPlant ExtractsPlants, EdibleStaphylococcus aureusUreaseAnti-Infective AgentsAntioxidantsEnzyme InhibitorsPhosphodiesterase InhibitorsPhytochemicalsPlant ExtractsUreaseScandix pecten-veneris L.; Phytochemical composition; Antioxidant activity; Antimicrobial potential; Enzyme inhibition

Identifiers

PMID29405040
PMCPMC5833326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.