Evidence map›Paper›PMID 29405039›Full record

ReviewJournal of Zhejiang University. Science. B

A review of the use of pteridophytes for treating human ailments.

Xavier-Ravi Baskaran, Antony-Varuvel Geo Vigila, Shou-Zhou Zhang, Shi-Xiu Feng, Wen-Bo Liao

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of Zhejiang University. Science. B. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
10.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 102 citations in OpenAlex.

  1. Plants (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Exploring wildFrontiers in nutrition · 2022
    Article
  12. Insights into the biosynthesis pathway of phenolic compounds in microalgae.Computational and structural biotechnology journal · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Pteridophytes in phytoremediation.Environmental geochemistry and health · 2020
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Xavier-Ravi BaskaranState Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.
Antony-Varuvel Geo VigilaDepartment of Zoology, St. Xavier's College, Palayamkottai, Tamil Nadu 627002, India.
Shou-Zhou ZhangShenzhen Key Laboratory of Southern Subtropical Plant Diversity, Fairy Lake Botanical Garden / Chinese Academy of Sciences, Shenzhen 518004, China.
Shi-Xiu FengShenzhen Key Laboratory of Southern Subtropical Plant Diversity, Fairy Lake Botanical Garden / Chinese Academy of Sciences, Shenzhen 518004, China.
Wen-Bo LiaoState Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.
Chinese Academy of Sciences · CNSun Yat-sen University · CNSt. Xavier's College (Autonomous)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this review was to explore the pharmacological activity of early tracheophytes (pteridophytes) as an alternative medicine for treating human ailments. As the first vascular plants, pteridophytes (aka, ferns and fern allies) are an ancient lineage, and human beings have been exploring and using taxa from this lineage for over 2000 years because of their beneficial properties. We have documented the medicinal uses of pteridophytes belonging to thirty different families. The lycophyte Selaginella sp. was shown in earlier studies to have multiple pharmacological activity, such as antioxidant, anti-inflammatory, anti-cancer, antidiabetic, antiviral, antimicrobial, and anti-Alzheimer properties. Among all the pteridophytes examined, taxa from the Pteridaceae, Polypodiaceae, and Adiantaceae exhibited significant medicinal activity. Based on our review, many pteridophytes have properties that could be used in alternative medicine for treatment of various human illnesses. Biotechnological tools can be used to preserve and even improve their bioactive molecules for the preparation of medicines against illness. Even though several studies have reported medicinal uses of ferns, the possible bioactive compounds of several pteridophytes have not been identified. Furthermore, their optimal dosage level and treatment strategies still need to be determined. Finally, the future direction of pteridophyte research is discussed.

Indexed as

PhytotherapyTracheophytaAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsHumansPhytochemicalsPlant ExtractsAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsPhytochemicalsPlant ExtractsPteridophyte; Fern; Alternative medicine; Selaginella; Human illness; Bioactive molecule

Identifiers

PMID29405039
PMCPMC5833325
OpenAlexW2794358064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.