ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2018
Underutilization of Treatment for Regional Gastric Cancer Among the Elderly in the USA.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Social determinants of health and upper gastrointestinal cancer outcomes in the United States: a systematic review.Frontiers in public health · 2024Pooled it
- Survival benefits from neoadjuvant treatment in gastric cancer: a systematic review and meta-analysis.Systematic reviews · 2022Pooled it
- Gastro-Esophageal Disorders of the Geriatric Population.The American journal of gastroenterology · 2025Article
- GCclassifier: An R package for the prediction of molecular subtypes of gastric cancer.Computational and structural biotechnology journal · 2024Article
- Survival analysis and prognostic model establishment of secondary osteosarcoma: a SEER-based study.Annals of medicine and surgery (2012) · 2024Article
- Access to cancer clinical trials for racialised older adults: an equity-focused rapid scoping review protocol.BMJ open · 2024Article
- Time to treatment disparities in gastric cancer patients in the United States of America: a comprehensive retrospective analysis.Frontiers in oncology · 2024Article
- Impact of Age on the Treatment and Survival in Esophagogastric Cancer.Annals of surgical oncology · 2023Article
- Associations of Education Level With Survival Outcomes and Treatment Receipt in Patients With Gastric Adenocarcinoma.Frontiers in public health · 2022Article
- Defining Undertreatment and Overtreatment in Older Adults With Cancer: A Scoping Literature Review.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020Article
- National Underutilization of Neoadjuvant Chemotherapy for Gastric Cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- Surgical Compliance and Outcomes in Gastric Cancer: a population-based cohort study.Journal of Cancer · 2019Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundIn the USA, a quarter of elderly patients do not receive any treatment for regional gastric cancer, which results in poorer outcomes. We sought to identify factors associated with undertreatment of regional gastric cancer in this population, as well as to assess overall survival in the undertreated population.
methodsElderly patients (aged ≥ 65 years) diagnosed with regional gastric cancer between 2001 and 2009 were identified from the Surveillance Epidemiology and End Results (SEER)-Medicare linked databases. Treatment was defined as receiving any medical or surgical therapy for gastric cancer. Logistic regression analysis was used to identify factors associated with failure to receive treatment. Overall survival was analyzed using the Kaplan-Meier method and Cox proportional hazard model.
resultsOf 5972 patients with regional gastric cancer, 1586 (26.5%) received no treatment. Median age was 78 years; 56.1% of patients were men. On multivariable analysis, the factors strongly associated with lack of therapy were age ≥ 80 years, black race, lower education level, and diagnosis before 2007. As expected, patients who received therapy had better overall survival (log-rank test, p < 0.001). Specifically, median survival and 5-year survival were 16.5 months and 20.5% for treated patients, compared with 9.1 months and 19.0% for untreated patients.
conclusionsElderly patients with gastric cancer have better overall 5-year survival after receiving treatment for their cancer. Disparities in the use of treatment for curable cancers are associated with older age, black race, lower educational level, and diagnosis before 2007.
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