Evidence map›Paper›PMID 29404842›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

Cardiorespiratory fitness and adiposity in breast cancer survivors: is meeting current physical activity recommendations really enough?

Alejandro Santos-Lozano, Javier Ramos, Alejandro Alvarez-Bustos, Blanca Cantos, Lidia B Alejo, Itziar Pagola, Ana Soria, Constanza Maximiano, Carmen Fiuza-Luces, Luisa Soares-Miranda and 2 more

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Neutrophil-to-lymphocyte ratio is associated with accelerometer-measured physical activity levels in breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  2. Article
  3. Article
  4. Cardiovascular Disease Risk in Survivors of Breast Cancer.Current treatment options in cardiovascular medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alejandro Santos-LozanoResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain.
Javier RamosDepartment of Medical Oncology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Alejandro Alvarez-BustosDepartment of Medical Oncology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Blanca CantosDepartment of Medical Oncology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Lidia B AlejoResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain.
Itziar PagolaResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain.
Ana SoriaDepartment of Oncology, Hospital Universitario de Fuenlabrada, Madrid, Spain.
Constanza MaximianoDepartment of Medical Oncology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Carmen Fiuza-LucesResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain.
Luisa Soares-MirandaResearch Center in Physical Activity Health and Leisure, Faculty of Sport, University of Porto, Rua Dr. Plácido Costa 91, 4200-450, Porto, Portugal. soaresmiranda@fade.up.pt.ORCID http://orcid.org/0000-0002-5929-4731
Alejandro LuciaResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain.
Ana Ruiz-CasadoDepartment of Medical Oncology, Hospital Universitario Puerta de Hierro, Madrid, Spain.

Funding

Fondo de Investigaciones Sanitarias PI15/00558Fundação para a Ciência e a Tecnologia SFRH/BPD/76947/2011
6 · The paper itself

Abstract

purposeBreast cancer (BC) survivors are becoming increasingly predisposed to cardiovascular disease (CVD) mortality. Low cardiorespiratory fitness and physical activity (PA) levels, as well as high values of adiposity indices, contribute to CVD risk. We evaluated adiposity, cardiorespiratory profile, and PA levels in two independent cohorts of BC survivors.

methodsData were collected from two groups (99% women) from different areas of Madrid (Spain): group 1, n = 110, age 51.4 ± 9.7 years, median time from diagnosis 365 days (95% confidence interval [CI], 354-401), and group 2, n = 93, age 54.7 ± 8.9 years, 1714 days (95% CI, 1502-1938). We estimated peak oxygen uptake (VO

resultsBoth groups had values of BMI in the overweight range (25.3 ± 4.3 and 27.1 ± 5.1 kg/m

conclusionsWe found a poor cardiorespiratory profile in two independent BC cohorts that differed in median time from diagnosis (as well in socioeconomic status), supporting the notion that implementation of PA (possibly focusing on vigorous PA) and dietary intervention is urgently needed in this patient population.

Indexed as

AdiposityBreast NeoplasmsCancer SurvivorsCardiorespiratory FitnessExerciseFemaleHumansMiddle AgedAccelerometryAnthracyclinesModerate–vigorous physical activityVO2peak

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.